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NCT04520490 · ClinicalTrials.gov registry record · Phase 3
Brain Activation and Satiety in Children 2
A Phase 3 study of Childhood Obesity, sponsored by Seattle Children's Hospital.
- Active
- Registry status
- Phase 3
- Development phase
- 63
- Enrollment target
- 1
- Study location
NCT04520490: Active Phase 3 study of Childhood Obesity, sponsored by Seattle Children's Hospital.
NCT04520490 is a Phase 3 study of Childhood Obesity that is active but no longer recruiting, run by Seattle Children's Hospital. The registered enrollment target is 63 participants, below the 559-participant average among 43 other Childhood Obesity trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04520490, a Phase 3 study of Childhood Obesity, is active but no longer recruiting, sponsored by Seattle Children's Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 63 participants
- Enrollment target
- 1
- Study location
Study Summary
Childhood obesity and related long-term effects are serious public health problems, but not all children with obesity do well in treatment. This study will test a new combination of family-based behavioral treatment (FBT) with a drug intervention using a glucagon-like peptide-1 receptor agonist (GLP-1RA) exenatide once weekly extended-release (ExQW, Bydureon®) in order to improve obesity intervention outcomes in 10-12-year-old children.
Primary Outcome
Body mass index (BMI) z-scores will be derived using CDC growth charts, using the LMS method, to allow for comparison of adiposity over time and across children who differ in age and sex.
Conditions Studied
Interventions
- DRUG Placebo
- BEHAVIORAL Family Based Behavioral Treatment
- DRUG Exenatide 2 mg [Bydureon]
Study Locations (1)
Washington
- Seattle Children's Hospital - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 63 participants |
| Start Date | 2021-01-28 |
| Est. Completion | 2026-02-12 |
| Phase | Phase 3 |
What the registry record for NCT04520490 still lists
NCT04520490 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 63 participants, a relatively small participant target, below the 559-participant average among 43 other Childhood Obesity trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Childhood Obesity appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT04520490 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT04520490 about?
NCT04520490 is a clinical study titled "Brain Activation and Satiety in Children 2". Childhood obesity and related long-term effects are serious public health problems, but not all children with obesity do well in treatment. This study will test a new combination of family-based behavioral treatment (FBT) with a drug intervention using a glucagon-like peptide-1 receptor agonist (GLP...
What is the current status of trial NCT04520490?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 63 participants. The study started on 2021-01-28. Estimated completion is 2026-02-12.
What conditions does trial NCT04520490 study?
This clinical trial studies the following conditions: Childhood Obesity.
What interventions are being tested in trial NCT04520490?
The interventions under investigation include: Placebo (DRUG), Family Based Behavioral Treatment (BEHAVIORAL), Exenatide 2 mg [Bydureon] (DRUG).
Who is sponsoring clinical trial NCT04520490?
This trial is sponsored by Seattle Children's Hospital, which has 168 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04520490 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Childhood Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04520490's enrollment target sits among peer trials
63 31st of 43 higher than 13 of 43 other Childhood Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Childhood Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome
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