Astellas Pharma Global Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Astellas Pharma Global Development sits in the top decile of US sponsors by registered trial count (#172 of 15,742 sponsors by registered trial count).

168 total trials 19 currently recruiting 121 completed early-phase tilt top decile by trial count

Astellas Pharma Global Development: 168 sponsored US clinical trials, 19 recruiting.

Astellas Pharma Global Development sponsors 168 registered US clinical trials on ClinicalTrials.gov, 19 of them currently recruiting, and 121 completed. 28 of these trials are in Phase 3-4 (later-stage) and 132 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy Volunteers, with 10 trials.

Top-decile sponsor footprint

Astellas Pharma Global Development ranks in the top decile of sponsors by registered trial count (#172 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 57/100

121 of 139 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (87.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

168 total, page 1 of 4

RECRUITING Phase 3

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

NCT07566156

RECRUITING Phase 1

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

NCT07488676

RECRUITING Phase 3

A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation

NCT07566052

RECRUITING Phase 2

A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder

NCT07475806

RECRUITING

A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults

NCT07425574

RECRUITING Phase 3

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

NCT07409272

RECRUITING Phase 1

A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

NCT07287995

RECRUITING Phase 1

A Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Healthy Adults

NCT07395024

RECRUITING Phase 1

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

NCT07024615

RECRUITING Phase 1

A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

NCT07140016

RECRUITING Phase 2

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

NCT07005154

RECRUITING Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

NCT06901531

RECRUITING

A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

NCT06779773

RECRUITING Phase 1

A Study to Evaluate the Effects of ASP5502 in Healthy Adults and Adults With Primary Sjögren's Syndrome

NCT06544642

RECRUITING Phase 1

A Study of ASP1002 in Adults for Treatment of Solid Tumors

NCT05719558

RECRUITING Phase 1

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

NCT05365581

RECRUITING Phase 1

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

NCT05083481

RECRUITING Phase 1

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

NCT04729114

RECRUITING Phase 2

A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

NCT02960022

ACTIVE NOT RECRUITING Phase 1

A Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer

NCT06396091

ACTIVE NOT RECRUITING

A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats

NCT06049797

ACTIVE NOT RECRUITING Phase 1

A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia

NCT05520567

ACTIVE NOT RECRUITING Phase 3

Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

NCT04223856

ACTIVE NOT RECRUITING Phase 2

A Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

NCT04225117

ACTIVE NOT RECRUITING Phase 2

A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer

NCT03816163

ACTIVE NOT RECRUITING Phase 3

A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).

NCT03653507

ACTIVE NOT RECRUITING Phase 2

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

NCT03505320

ACTIVE NOT RECRUITING Phase 3

A Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy in Adults With Gastric Cancer.

NCT03504397

ACTIVE NOT RECRUITING Phase 1

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

NCT03288545

COMPLETED

Experiment to Assess Preferences for Novel Hormonal Therapy and Androgen-deprivation Therapy in Prostate Cancer Patients

NCT06500741

TERMINATED Phase 1

A Study of ASP1012 in Adults With Solid Tumors

NCT06171178

COMPLETED Phase 3

A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery in People With or Without Kidney Disease

NCT05999747

COMPLETED Phase 3

A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery

NCT05754333

TERMINATED Phase 1

A Study of ASP2074 in Adults With Solid Tumors

NCT05646797

COMPLETED Phase 3

Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy

NCT05536297

COMPLETED Phase 1

A Study About How ASP5354 Affects the Body in Healthy Adults and in Adults Whose Kidneys do Not Work Well

NCT05495581

TERMINATED Phase 1

A Study to Find a Suitable Dose of ASP8731 and Check for Medical Problems at Each Dose in Healthy Adults

NCT05167526

COMPLETED Phase 1

A Study to Learn How [14C]ASP0367 is Processed by the Body in Healthy Men

NCT05217901

TERMINATED Phase 1

Study of ASP0739 Alone and With Pembrolizumab in Advanced Solid Tumors With NY-ESO-1 Expression Participants

NCT04939701

COMPLETED Phase 1

A Study of ASP0367 in People With Kidneys That do Not Work Well and in Healthy People

NCT05117294

TERMINATED Phase 1

A Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (NMIBC)

NCT05014139

COMPLETED Phase 1

Study of ASP7517 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors Expressing WT1 Antigen

NCT04837196

COMPLETED Phase 1

A Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function

NCT04942964

COMPLETED

Survey Based Discrete Choice Experiment Study in Prostate Cancer (DECIDER) Study

NCT05381311

TERMINATED Phase 1

A Study to Evaluate ASP0367 in Participants With Reduced Maximum Oxygen Uptake Due to Poor Systemic Oxygen Extraction

NCT04855201

COMPLETED Phase 1

A Study to Investigate the Effect of Severe Renal Impairment on Gilteritinib Compared to Healthy Participants With Normal Renal Function

NCT04699877

COMPLETED Phase 1

A Study to Assess the Effect of Food With Fezolinetant in Healthy Female Participants

NCT04641260

TERMINATED Phase 1

A Study to Assess ASP0598 Otic Solution Following Topical Application in the Ear in Subjects With Chronic Tympanic Membrane Perforation (CTMP)

NCT04305184

TERMINATED Phase 1

A Study of Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

NCT04240002

COMPLETED Phase 1

A Study to Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Hepatic Function

NCT04482270

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What is open in the Astellas Pharma Global Development pipeline

19 recruiting of 168 indexed (11% open); 121 completed (72%).

Phase mix: 28 late (III/IV) vs 132 early (I/II) (early-phase heavy).

Top condition: Healthy Volunteers (10 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Astellas Pharma Global Development: open-pipeline peers nationwide

Peers matched on 168 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

Astellas Pharma Global Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 100120140160180200 0%5%10%15%20% Total trials Recruiting share Astellas Pharma Global DevelopmentBausch Health AmericasSeattle Children's HospitalSumitomo Pharma AmericaUniversity of New MexicoSt. Louis UniversityUniversity of ConnecticutChildren's Mercy Hospital Kansas CityAlbert Einstein College of Medicine
Astellas Pharma Global Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Astellas Pharma Global Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 168 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this Astellas Pharma Global Development page

168 registered trials is a research-attention snapshot, not an endorsement of Astellas Pharma Global Development or any single study.

  • 19 of Astellas Pharma Global Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy Volunteers is the condition Astellas Pharma Global Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy Volunteers trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Astellas Pharma Global Development pipeline card: 168 registered trials from official public datasets.Report a data error.