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ClinicalTrials.gov 9 recruiting now early-phase tilt small index

Wilms Tumor: early-phase trial registry

9 of 15 indexed Wilms Tumor trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 9 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Wilms Tumor: 15 US clinical trials tracked, 9 recruiting.

Wilms Tumor is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Baylor College of Medicine, running 4 of these trials.

Enrollment posture brief

Registry condition wilms-tumor

OPEN 9 | RECR 60% | LATE 0 | EARLY 13 | RANK #1140 | SPON 4

Nearest open-share peer: Abuse, Drug (60% recruiting · 5 trials)

Wilms Tumor (this)60%Advanced Lung Non-Small Cell53.3%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Wilms Tumor

Wilms Tumor lists 9 open slots (60% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Wilms Tumor on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Wilms Tumor is recruiting above its size-band peers.

    9 of 15 indexed trials (60%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Wilms Tumor research.

    Baylor College of Medicine accounts for 4 of 15 trials (26.7%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Wilms Tumor trials plan to enrol fewer than 100 people.

    Median target enrolment is 28 among the 15 trials that report a genuine target (sentinel values excluded). 12 of those (80%) plan for fewer than 100 participants.

  4. Wilms Tumor research is mostly interventional.

    13 interventional and 2 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 111Phase 22

Open and recent trials

15 total, page 1 of 1

RECRUITING 3,400 participants

International PPB/DICER1 Registry

Children's Hospitals and Clinics of Minnesota

NCT03382158

RECRUITING Phase 2 260 participants

Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation

St. Jude Children's Research Hospital

NCT04968990

RECRUITING Phase 2 45 participants

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT05985161

RECRUITING Phase 1 32 participants

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

NCT04897321

RECRUITING Early Phase 1 28 participants

Pencil Beam Scanning in Patients With Renal Tumors

Children's Hospital of Philadelphia

NCT03810651

RECRUITING Phase 1 24 participants

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Baylor College of Medicine

NCT04715191

RECRUITING Phase 1 21 participants

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

Baylor College of Medicine

NCT06198296

RECRUITING Phase 1 21 participants

Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

Seattle Children's Hospital

NCT07148050

RECRUITING Phase 1 18 participants

Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)

Children's National Research Institute

NCT07172958

ACTIVE NOT RECRUITING Phase 1 68 participants

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

NCT04483778

ACTIVE NOT RECRUITING Phase 1 44 participants

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

NCT03618381

ACTIVE NOT RECRUITING Phase 1 14 participants

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Baylor College of Medicine

NCT04377932

ACTIVE NOT RECRUITING Phase 1 12 participants

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

Baylor College of Medicine

NCT05103631

COMPLETED 101 participants

iCAT for Recurrent/Refractory/HR Solid Tumors

Dana-Farber Cancer Institute

NCT01853345

COMPLETED Phase 1 18 participants

HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors

Timothy Cripe

NCT00931931

Phase Distribution

PhaseTrial count
Phase 1 11
Phase 2 2

Named interventions

Most-linked intervention names on Wilms Tumor records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

HSV1716 Biological
1 trials
AGAR T cells Genetic
1 trials
second generation 4-1BBζ EGFR806-EGFRt and a second generation 4 1BBζ CD19-Her2tG Biological
1 trials
second generation 4-1BBζ EGFR806-EGFRt Biological
1 trials
CATCH T cells Genetic
1 trials
second generation 4-1BBζ B7H3-EGFRt-DHFR(selected) and a second generation 4-1BBζ CD19-Her2tG Biological
1 trials
second generation 4-1BBζ B7H3-EGFRt-DHFR Biological
1 trials
Partial Nephrectomy Procedure
1 trials

US sites by state

Facility locations filed on Wilms Tumor trials. A trial with sites in several states counts in each.

Texas 4 trials
Washington 3 trials
Tennessee 2 trials
Ohio 2 trials
New York 2 trials
Massachusetts 2 trials
California 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Wilms Tumor page

15 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Wilms Tumor condition card totals 15 registered trials; most-linked intervention HSV1716; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.