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2026 data Public-data reference. official source

Concussion, Brain

Open-data reference.

21 US clinical trials · 12 currently recruiting

Active & Recent Trials

RECRUITING 500 participants

Risk Stratification in Children With Concussion

Duke University

NCT05825027

RECRUITING NA 360 participants

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

Johns Hopkins University

NCT05663034

RECRUITING NA 304 participants

Concussion Health Improvement Program

Seattle Children's Hospital

NCT06036147

RECRUITING Phase 2 216 participants

Modulating Exercise Dosage to Improve Concussion Recovery

University of Colorado, Denver

NCT05434130

RECRUITING Phase 2 150 participants

BCAAs in Concussion 2.0

Akiva Cohen

NCT06829498

RECRUITING NA 130 participants

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

University of North Carolina, Chapel Hill

NCT05320822

RECRUITING Phase 2 75 participants

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

University of California, Los Angeles

NCT06073886

RECRUITING Phase 2 75 participants

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

University of Texas Southwestern Medical Center

NCT05446584

RECRUITING NA 72 participants

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

University of California, San Diego

NCT05682677

RECRUITING NA 46 participants

The Influence of Prescribed Exercise on Pain Related Fear Following Concussion in Collegiate Athletes

University of Virginia

NCT06246669

RECRUITING Phase 2 42 participants

Growth Hormone Replacement Therapy for Retried Professional Football Players

Center for Neurological Studies

NCT04121780

RECRUITING NA 20 participants

Creatine Supplementation in Concussion Recovery

San Diego State University

NCT06208813

ACTIVE NOT RECRUITING 660 participants

Follow-up of MTBI Patients Discharged from the ED Using Standard Clinical Triage Including BrainScope One

BrainScope Company

NCT04279431

ACTIVE NOT RECRUITING NA 200 participants

Mobile Subthreshold Exercise Program for Concussion--R01

Seattle Children's Hospital

NCT04688255

COMPLETED 268 participants

Objective Brain Function Assessment of mTBI/Concussion

BrainScope Company

NCT03963804

COMPLETED NA 251 participants

Role of Rehabilitation in Concussion Management: A Randomized Controlled Trial

University of North Carolina, Chapel Hill

NCT02988596

COMPLETED NA 98 participants

Developing an Implementation Strategy for Post-concussion Communication With Low Health Literacy Parents in the Emergency Department

Seattle Children's Hospital

NCT04112914

COMPLETED NA 72 participants

Concussion Prevention in Female Soccer Athletes

Children's Hospital Medical Center, Cincinnati

NCT03014492

COMPLETED NA 60 participants

Salivary Biomarkers for Concussion Recovery

State University of New York at Buffalo

NCT05379920

COMPLETED NA 50 participants

Efficacy of Brock String Therapy Post Concussion

University of Pittsburgh

NCT04076657

COMPLETED NA 41 participants

The Effects of a Sub-maximal Exercise Program on Adolescents Who Sustained a Concussion

Boston Children's Hospital

NCT03170856

Phase Distribution

PhaseTrial count
Phase 2 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Concussion, Brain Trial Landscape

ClinicalTrials.gov lists 21 US studies indexed under Concussion, Brain, and 12 of those are currently open to recruitment — roughly 57% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Concussion, Brain shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Concussion, Brain is led by Seattle Children's Hospital with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 21 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Concussion, Brain?

PlainTrial tracks 21 US clinical trials for Concussion, Brain, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Concussion, Brain?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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