National Institute on Aging (NIA)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute on Aging (NIA) sits in the top decile of US sponsors by registered trial count (#209 of 15,742 sponsors by registered trial count).

131 total trials 12 currently recruiting 103 completed early-phase tilt top decile by trial count

National Institute on Aging (NIA): 131 sponsored US clinical trials, 12 recruiting.

National Institute on Aging (NIA) sponsors 131 registered US clinical trials on ClinicalTrials.gov, 12 of them currently recruiting, and 103 completed. 18 of these trials are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Aging, with 7 trials.

Top-decile sponsor footprint

National Institute on Aging (NIA) ranks in the top decile of sponsors by registered trial count (#209 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 62/100

103 of 116 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

131 total, page 1 of 3

RECRUITING NA

Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial

NCT06274749

RECRUITING

Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging

NCT07099053

RECRUITING

Pediatric Neuroimaging

NCT06912724

RECRUITING

Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide

NCT06269653

RECRUITING

Collection of Bone Marrow Aspirate From Normal Volunteers

NCT03949647

RECRUITING

Taste Bud-Derived Stem Cells in Humans

NCT03366168

RECRUITING

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

NCT02339012

RECRUITING

Baltimore Longitudinal Study of Aging

NCT00233272

RECRUITING

Development of 3T Magnetic Resonance Research Methods for NIA Studies

NCT01324206

RECRUITING

Genetic Characterization of Movement Disorders and Dementias

NCT02014246

RECRUITING

Tissue Procurement for Biomedical Research

NCT00182858

RECRUITING

Cytapheresis of Volunteer Donors

NCT00104325

ACTIVE NOT RECRUITING

A Clinical Observational Study of SARS-CoV-2 Specific CD8 T-Cell Responses to COVID-19 Vaccines in Humans

NCT04852289

ACTIVE NOT RECRUITING

Identification and Characterization of SARS-CoV-2 Specific CD8 T Cells in Humans

NCT04565067

ACTIVE NOT RECRUITING

Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS)

NCT01323322

COMPLETED NA

Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia

NCT06273917

COMPLETED NA

Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults 55 Years Old or Older

NCT04421014

COMPLETED Phase 1

Sodium-glucose Co Transporter 2 (sGLT2) Inhibitor and Endogenous Ketone Production

NCT03852901

COMPLETED

Study of Skin Cells That Stop Replicating (Senescent) During Wound Healing

NCT02755584

TERMINATED Phase 1

Resveratrol and Cardiovascular Health in the Elderly

NCT01842399

COMPLETED NA

Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain Function

NCT02460783

COMPLETED Phase 1

The Role of Phosphodiesterase Inhibitors in Incretin Secretion

NCT02363335

COMPLETED Phase 1

Bisnorcymserine in Healthy Adult Volunteers

NCT01747213

COMPLETED

Calcium Channel Splice Variant Expression in Cardiovascular Disease and Aging

NCT00251615

COMPLETED Phase 1

Mechanisms Accounting for Unexplained Anemia in the Elderly

NCT01572506

COMPLETED Phase 1

The Role of Endocannabinoids in Insulin Production and Action

NCT01517100

TERMINATED

Age-Related Changes in Body Composition

NCT01517113

COMPLETED Phase 1

Initial Study of Fenoterol as a Treatment for Heart Failure

NCT01440335

COMPLETED

CARDIA Brain MRI Substudy

NCT01273311

TERMINATED Phase 2

A Pilot Clinical Trial of Exendin-4 in Alzheimer's Disease

NCT01255163

TERMINATED NA

Muscle Biopsies in Healthy Volunteers

NCT01431677

COMPLETED Phase 1

Safety and Tolerability of the Derma Vax(Trademark) Clinical Intradermal Electroporation System in Healthy Subjects

NCT01324843

COMPLETED Phase 1

The Relationship Between Uric Acid and Inflammatory Markers

NCT01323335

TERMINATED

Androgen Deprivation Therapy Study

NCT00743327

TERMINATED

AMS Study: Inflammatory and Biomechanical Contributors to Arthritis Development Following Arthroscopic Meniscectomy

NCT00752271

TERMINATED

A Prospective Study of Postpartum Depression in Women With Major Depression

NCT01328613

COMPLETED NA

Improving Depression Treatment for Older Minority Adults

NCT00570427

COMPLETED Phase 3

Exercise, Executive Processes and the Aging Brain

NCT00430976

COMPLETED Phase 1

Growth Hormone Administration and the Human Immune System

NCT00663611

COMPLETED NA

Proximity Alarms to Reduce Patient Falls

NCT00183053

COMPLETED NA

Breathe: Slow Paced Breathing to Lower Blood Pressure

NCT00328016

COMPLETED NA

An Intervention to Increase Physical Activity Among African American Women

NCT00473044

COMPLETED Phase 1

Anti-Oxidant Treatment of Alzheimer's Disease

NCT00117403

TERMINATED

Etiology of Anemia

NCT00302939

COMPLETED Phase 2

REVEAL: Reduction of Infarct Expansion and Ventricular Remodeling With Erythropoietin After Large Myocardial Infarction

NCT00378352

COMPLETED NA

Caminemos! Trial to Increase Walking Among Sedentary Older Latinos

NCT00183014

COMPLETED

Memory Imaging of Normal Aging

NCT00315575

COMPLETED

A Study of the Function of Hormones Present In Taste Buds

NCT00233298

COMPLETED

Alzheimer's Caregiver Communication Study

NCT00182988

COMPLETED Phase 2

Osteopuncture for Osteoarthritis-Associated Knee Pain & Disability

NCT00417313

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Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 20
Phase 3 14
Phase 4 4

What is open in the National Institute on Aging (NIA) pipeline

12 recruiting of 131 indexed (9% open); 103 completed (79%).

Phase mix: 18 late (III/IV) vs 38 early (I/II) (early-phase heavy).

Top condition: Aging (7 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute on Aging (NIA): open-pipeline peers nationwide

Peers matched on 131 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

National Institute on Aging (NIA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150 5%10%15%20%25% Total trials Recruiting share National Institute on Aging (NIA)Rhode Island HospitalGeorge Washington UniversityUniversity of Illinois at Urbana-ChampaignJazz PharmaceuticalsAlkermesDBV TechnologiesFlorida Gulf Coast UniversityGenfit
National Institute on Aging (NIA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute on Aging (NIA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 131 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

What to do with this National Institute on Aging (NIA) page

131 registered trials is a research-attention snapshot, not an endorsement of National Institute on Aging (NIA) or any single study.

  • 12 of National Institute on Aging (NIA)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Aging is the condition National Institute on Aging (NIA) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Aging trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institute on Aging (NIA) pipeline card: 131 registered trials from official public datasets.Report a data error.