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NCT06273917 · ClinicalTrials.gov registry record · NA

Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia

A NA study, sponsored by National Institute on Aging (NIA).

Completed
Registry status
NA
Development phase
300
Enrollment target

NCT06273917: Completed NA study, sponsored by National Institute on Aging (NIA).

NCT06273917 is a NA study that has completed, run by National Institute on Aging (NIA). The registered enrollment target is 300 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (79% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06273917, a NA study, has completed, sponsored by National Institute on Aging (NIA).

COMPLETED
Registry status
NA
Development phase
300 participants
Enrollment target

Study Summary

Aim 1: To demonstrate the feasibility by determining proportion of completed medication reconciliation, Central Nervous System active Potentially Inappropriate Medication (CNS PIM) use among patients with Alzheimer's Disease and Related Dementias (ADRD) and Mild Cognitive Impairment (MCI) in the emergency department (ED), and communication between ED clinical pharmacists and outpatient prescribers. Aim 2: To demonstrate the feasibility of collecting the primary and secondary outcomes for a subsequent study. The future primary outcome will be reduction in CNS PIMs 90 days after an ED visit. Secondary outcomes will include outpatient follow-up, repeat ED visits, and hospitalizations during the 90 days following an ED visit. Aim 3: To demonstrate the acceptability of the PRIDE intervention to outpatient clinicians using the Acceptability of Intervention Measure and qualitative analysis of responses.

Primary Outcome

This will be determined if the ED pharmacist sends an electronic message through the EHR to the outpatient prescriber with de-prescribing recommendations for patients who are taking CNS PIMs. This will be performed on Day 0 in the Emergency Department.

Interventions

  • OTHER PRIDE

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2024-07-09
Est. Completion 2025-10-31
Phase NA
National Institute on Aging (NIA)

131 total trials

What the finished NCT06273917 record still lists

NCT06273917 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (79% lower).

The record links to 0 conditions, and to 1 intervention - of which PRIDE is the first listed.

NCT06273917 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06273917 about?

NCT06273917 is a clinical study titled "Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia". Aim 1: To demonstrate the feasibility by determining proportion of completed medication reconciliation, Central Nervous System active Potentially Inappropriate Medication (CNS PIM) use among patients with Alzheimer's Disease and Related Dementias (ADRD) and Mild Cognitive Impairment (MCI) in the eme...

What is the current status of trial NCT06273917?

This trial is currently completed. It is a NA study. The enrollment target is 300 participants. The study started on 2024-07-09. Estimated completion is 2025-10-31.

What interventions are being tested in trial NCT06273917?

The interventions under investigation include: PRIDE (OTHER).

Who is sponsoring clinical trial NCT06273917?

This trial is sponsored by National Institute on Aging (NIA), which has 131 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06273917's enrollment target sits among peer trials

300 330th of 2000 higher than 1,630 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06273917, the US trial registry maintained by the National Library of Medicine. NCT06273917 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.