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NCT02339012 · ClinicalTrials.gov registry record

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

A clinical trial of Healthy Volunteers and Non-Healthy/Non-Frail, sponsored by National Institute on Aging (NIA).

Recruiting
Registry status
900
Enrollment target
1
Study location

NCT02339012: Recruiting study of Healthy Volunteers and Non-Healthy/Non-Frail, sponsored by National Institute on Aging (NIA).

NCT02339012 is a study of Healthy Volunteers and Non-Healthy/Non-Frail that is actively recruiting participants, run by National Institute on Aging (NIA). The registered enrollment target is 900 participants, above the 479-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (88% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02339012, a study of Healthy Volunteers and Non-Healthy/Non-Frail, is actively recruiting participants, sponsored by National Institute on Aging (NIA).

RECRUITING
Registry status
900 participants
Enrollment target
1
Study location

Study Summary

Background: \- Biomarkers are substances in people s blood and tissues. They help researchers understand diseases and signs of aging. Scientists want to do more research on biomarkers to find ways to improve quality of life in old age. Objective: \- To learn more about biomarkers and their relationship to aging. Eligibility: \- Adults at least 20 years old who weigh at least 110 pounds and have a body mass index below 30. They must agree that their genetic samples can be collected, studied, and stored. Design: * Participants will be screened with medical history, physical exam, EKG and blood and urine tests. * Participants will have 3-day visits. They will return every 2 years. * All visits include: * Blood and urine collection * Physical performance tests * Health questionnaires * Memory and problem-solving tests * Magnetic Resonance Imaging (MRI) and Computerized Tomography (CT) scans. * Muscle metabolism/ exercise tests * Taste strips * Muscle and/or skin biopsies/ red light therapy * Retinal imaging/ eye tracking * Sleep study * ODD visits also include: * Cytapheresis * Bone marrow aspirate * EVEN visits also include: * Hyperglycemic CLAMP * Lumbar Puncture (LP) * Continuous Glucose Monitor (CGM)

Primary Outcome

measurement of epigenetic, gene expression, and protein biomarkers

Study Locations (1)

Maryland

  • National Institute of Aging, Clinical Research Unit - Baltimore

Trial Details

FieldValue
Enrollment Target 900 participants
Start Date 2015-03-15
Est. Completion 2099-12-31
National Institute on Aging (NIA)

131 total trials

What NCT02339012 shows while recruiting

NCT02339012 is an observational study that tracks outcomes without assigning an intervention. The registered 900 participants enrollment target is mid-sized for trials with a published cap, above the 479-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (88% higher).

The record links to 3 conditions, with Healthy Volunteers appearing as the primary indexed condition, and to 0 interventions.

NCT02339012 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT02339012 about?

NCT02339012 is a clinical study titled "Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)". Background: \- Biomarkers are substances in people s blood and tissues. They help researchers understand diseases and signs of aging. Scientists want to do more research on biomarkers to find ways to improve quality of life in old age. Objective: \- To learn more about biomarkers and their relati...

What is the current status of trial NCT02339012?

This trial is currently recruiting. The enrollment target is 900 participants. The study started on 2015-03-15. Estimated completion is 2099-12-31.

What conditions does trial NCT02339012 study?

This clinical trial studies the following conditions: Healthy Volunteers, Non-Healthy/Non-Frail, Frail.

Who is sponsoring clinical trial NCT02339012?

This trial is sponsored by National Institute on Aging (NIA), which has 131 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02339012 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteers

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02339012's enrollment target sits among peer trials

900 20th of 283 higher than 264 of 283 other Healthy Volunteers trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02339012, the US trial registry maintained by the National Library of Medicine. NCT02339012 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.