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NCT01440335 · ClinicalTrials.gov registry record · Phase 1
Initial Study of Fenoterol as a Treatment for Heart Failure
A Phase 1 study, sponsored by National Institute on Aging (NIA).
- Completed
- Registry status
- Phase 1
- Development phase
- 29
- Enrollment target
NCT01440335 is a Phase 1 study that has completed, run by National Institute on Aging (NIA). The registered enrollment target is 29 participants.
The verdict
NCT01440335, a Phase 1 study, has completed, sponsored by National Institute on Aging (NIA).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 29 participants
- Enrollment target
Study Summary
Background: \- Fenoterol has been used to treat asthma by opening up the airways in the lungs. It also increases the heart rate without significantly increasing blood pressure. This means that it may help improve heart function by boosting the heart's output. Researchers have developed a different form of the drug that may be given to individuals with heart trouble. This new form needs more testing. It is especially important to compare the new form with the original form of the drug used to treat asthma. Objectives: \- To compare how safe and effective two different forms of Fenoterol are in improving heart function. Eligibility: \- Healthy people between 21 and 60 years of age who have no history of heart disease. Design: * People will be screened with a medical history, physical exam, blood and urine tests, and heart function studies. * Those in the study will have two 36-hour inpatient study visits. At each visit, they will have a physical exam and blood and urine tests. They will fast overnight and then receive one of the two forms of Fenoterol first thing in the morning. They will not know whether they are getting the original or the modified form of the drug. After receiving the drug, they will provide frequent blood and urine samples for 24 hours. They will have a final exam before being discharged. * Those who take part in the study will have a followup visit 5 to 7 days after the end of each study visit. They will provide more blood and urine samples and have a physical exam.
Interventions
- DRUG Oral R,R'-Fenoterol
- DRUG Oral Racemic Fenoterol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2011-07-10 |
| Est. Completion | 2014-04-15 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01440335
The ClinicalTrials.gov registry entry for NCT01440335 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute on Aging (NIA), which has 131 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Oral R,R'-Fenoterol is the first listed.
NCT01440335 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01440335 about?
NCT01440335 is a clinical study titled "Initial Study of Fenoterol as a Treatment for Heart Failure". Background: \- Fenoterol has been used to treat asthma by opening up the airways in the lungs. It also increases the heart rate without significantly increasing blood pressure. This means that it may help improve heart function by boosting the heart's output. Researchers have developed a different ...
What is the current status of trial NCT01440335?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 29 participants. The study started on 2011-07-10. Estimated completion is 2014-04-15.
What interventions are being tested in trial NCT01440335?
The interventions under investigation include: Oral R,R'-Fenoterol (DRUG), Oral Racemic Fenoterol (DRUG).
Who is sponsoring clinical trial NCT01440335?
This trial is sponsored by National Institute on Aging (NIA), which has 131 total clinical trials registered on ClinicalTrials.gov.
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