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NCT02755584 · ClinicalTrials.gov registry record
Study of Skin Cells That Stop Replicating (Senescent) During Wound Healing
A clinical trial, sponsored by National Institute on Aging (NIA).
- Completed
- Registry status
- 75
- Enrollment target
NCT02755584: Completed study, sponsored by National Institute on Aging (NIA).
NCT02755584 is a clinical trial that has completed, run by National Institute on Aging (NIA). The registered enrollment target is 75 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02755584 has completed, sponsored by National Institute on Aging (NIA).
- COMPLETED
- Registry status
- 75 participants
- Enrollment target
Study Summary
Background: Cellular senescence is the aging of cells. It is a complex process that may be connected with aging and age-related diseases. It is unknown if these cells appear around wound sites in humans a few days after skin injury and if there are differences in young and old individuals. This study is being done to look at how cells in your body respond to small skin wounds. This information may help treat age-related diseases. Objective: To study how cells in the body respond to small skin wounds. Eligibility: Healthy adults ages 20-39 or 70+ Design: Participants will be screened with medical history, physical exam, and blood sample. They will fast before the screening visit. Women will have a urine pregnancy test. Participants will have 3 study visits over about 3 weeks. Visits 1 and 2: Participants will fast before and have blood taken. Women will have a urine test. All participants will have 2 skin biopsies. A spot on the upper arm will be numbed. Two small pieces of skin will be removed. They will keep the area covered until the next visit. Visit 3: Participants will have their vital signs taken. Their biopsy wounds will be measured and photographed.
Primary Outcome
Understanding the physiological role of senescent cells is critically important for understanding aging and age related diseases. Our preliminary results showed that there may be a difference in rate of granulation tissue formation with ethnicity.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2016-06-30 |
| Est. Completion | 2021-04-15 |
What the finished NCT02755584 record still lists
NCT02755584 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02755584 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02755584 about?
NCT02755584 is a clinical study titled "Study of Skin Cells That Stop Replicating (Senescent) During Wound Healing". Background: Cellular senescence is the aging of cells. It is a complex process that may be connected with aging and age-related diseases. It is unknown if these cells appear around wound sites in humans a few days after skin injury and if there are differences in young and old individuals. This stu...
What is the current status of trial NCT02755584?
This trial is currently completed. The enrollment target is 75 participants. The study started on 2016-06-30. Estimated completion is 2021-04-15.
Who is sponsoring clinical trial NCT02755584?
This trial is sponsored by National Institute on Aging (NIA), which has 131 total clinical trials registered on ClinicalTrials.gov.
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