National Institute on Aging (NIA)

131 total trials 12 currently recruiting 103 completed

National Institute on Aging (NIA) sponsors 131 registered US clinical trials on ClinicalTrials.gov, 12 of them currently recruiting, and 103 completed. 18 of these trials are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Aging, with 7 trials.

Trial Pipeline

131 total, page 2 of 3

COMPLETED NA

Memory Aid for Informed Consent in Alzheimer's Research

NCT00105612

COMPLETED

Serum, Dietary and Supplemental Vitamin D's Association With Cognitive Decline

NCT03320109

COMPLETED NA

Comparison of an Easy to Read Advance Directive Versus a Standard Advance Directive

NCT00328055

COMPLETED NA

Sleepiness and the Risk of Falling

NCT00383357

TERMINATED Phase 2

Idiopathic Anemia of Aging (IAA)

NCT00104169

COMPLETED Phase 2

Bryostatin 1 and Rituximab in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia

NCT00087425

TERMINATED

Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study)

NCT00246493

COMPLETED NA

Age, Lifestyle, Muscle Mechanisms in Insulin Resistance

NCT00971594

COMPLETED Phase 2

Huperzine A in Alzheimer's Disease

NCT00083590

COMPLETED Phase 1

The LIFE Study: Lifestyle Interventions and Independence for Elders, Pilot

NCT00116194

COMPLETED

Fast Food Study: Assessment of the Effects of Fast-Food on Inflammatory Markers

NCT00233311

COMPLETED Phase 2

Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial.

NCT00104572

COMPLETED Phase 2

Hormone Replacement Therapy (HRT) Website Tool

NCT00319072

COMPLETED Phase 2

The Effects of Metformin on Blood Vessel Structure and Function

NCT00105066

COMPLETED NA

ABC Trial: Awakening and Breathing Controlled

NCT00097630

COMPLETED

Lymphoma Follow-up

NCT00744120

COMPLETED

Effects of Hormonal Infertility Treatment on Cognition in Pre-Menopausal Women

NCT00113867

COMPLETED Phase 2

The TLC2 (Teaching Healthy Lifestyles to Caregivers 2)/CALM (Counseling Advice for Lifestyle Management) Study

NCT00131105

COMPLETED

Forearm Vascular Relaxation

NCT00182923

COMPLETED

Risk Evaluation and Education for Alzheimer's Disease (REVEAL) II

NCT00089882

COMPLETED

Early Markers of Cognitive Change and Alzheimer s Disease

NCT01867346

COMPLETED

The Genetic Characterization of Dementia

NCT01867359

TERMINATED

Early Markers of Alzheimer's Disease: Structural and Functional Brain Changes

NCT01867372

COMPLETED Phase 1

Analysis of Atropine and Propranolol Induced Changes

NCT00251602

COMPLETED

Salt Study: Inhibited Breathing Pattern and Sodium Inhibitors in Sodium Sensitivity of Blood Pressure

NCT00800228

COMPLETED

Screening Protocol to Evaluate Volunteers for NIA Approved Studies

NCT02091271

COMPLETED Phase 1

GIP: Glucose-dependent Insulinotropic Peptide

NCT00239707

COMPLETED

Studies of Heritable Disorders of Connective Tissue

NCT00270686

COMPLETED Phase 3

VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)

NCT00056225

TERMINATED

Osteoarthritis and Body Composition: Evaluation of Systematic Mediators

NCT00771082

COMPLETED Phase 3

Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study

NCT00053599

COMPLETED NA

Dietary Energy Restriction and Metabolic Aging in Humans

NCT00183027

COMPLETED Phase 2

HORMA: Hormonal Regulators of Muscle and Metabolism in Aging

NCT00183040

COMPLETED

MIRAGE: Multi-Institutional Research in Alzheimer's Genetic Epidemiology

NCT00239759

COMPLETED Phase 3

Effects of Dehydroepiandrosterone (DHEA) in Humans

NCT00182975

COMPLETED NA

The Immune Function Intervention Trial

NCT00548990

COMPLETED

Collection of Bone Marrow Aspirate From Volunteer Donors

NCT00183066

COMPLETED Phase 4

Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)

NCT00043849

COMPLETED Phase 1

CALERIE (Tufts) - Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy

NCT00099099

COMPLETED NA

CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

NCT00099151

COMPLETED Phase 1

CALERIE (Washington University): Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy

NCT00099138

COMPLETED NA

Race, Menopause and Metabolism After Exercise and Diet

NCT00882141

COMPLETED NA

GRACE: Geriatric Resources for Assessment and Care of Elders

NCT00182962

COMPLETED Phase 2

Pioglitazone in Alzheimer Disease

NCT00982202

COMPLETED Phase 4

Testosterone Effects on Bone and Frailty

NCT00182871

COMPLETED Phase 3

Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification

NCT00183001

COMPLETED NA

The HIP Impact Protection Program (HIP PRO)

NCT00058864

COMPLETED Phase 3

A Comparison of Weighted Vest Exercise and Strength Training

NCT00158119

COMPLETED Phase 2

Shingles: Immune Effects of Tai Chi

NCT00118885

COMPLETED NA

Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans

NCT00099697

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Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 20
Phase 3 14
Phase 4 4

What the Pipeline for National Institute on Aging (NIA) Shows

According to the ClinicalTrials.gov registry, National Institute on Aging (NIA) is linked to 131 US clinical trials across every stage of research activity. Of those, 12 studies are currently recruiting, about 9% of the sponsor's indexed portfolio, and 103 are already marked complete, representing roughly 79% of the total.

The phase mix for National Institute on Aging (NIA) reports 18 late-stage studies (Phase 3 and Phase 4 combined) and 38 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute on Aging (NIA) is Aging with 7 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.