National Institute on Aging (NIA)
National Institute on Aging (NIA) sponsors 131 registered US clinical trials on ClinicalTrials.gov, 12 of them currently recruiting, and 103 completed. 18 of these trials are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Aging, with 7 trials.
Trial Pipeline
131 total, page 2 of 3
Memory Aid for Informed Consent in Alzheimer's Research
NCT00105612
Serum, Dietary and Supplemental Vitamin D's Association With Cognitive Decline
NCT03320109
Comparison of an Easy to Read Advance Directive Versus a Standard Advance Directive
NCT00328055
Sleepiness and the Risk of Falling
NCT00383357
Idiopathic Anemia of Aging (IAA)
NCT00104169
Bryostatin 1 and Rituximab in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
NCT00087425
Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study)
NCT00246493
Age, Lifestyle, Muscle Mechanisms in Insulin Resistance
NCT00971594
Huperzine A in Alzheimer's Disease
NCT00083590
The LIFE Study: Lifestyle Interventions and Independence for Elders, Pilot
NCT00116194
Fast Food Study: Assessment of the Effects of Fast-Food on Inflammatory Markers
NCT00233311
Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial.
NCT00104572
Hormone Replacement Therapy (HRT) Website Tool
NCT00319072
The Effects of Metformin on Blood Vessel Structure and Function
NCT00105066
ABC Trial: Awakening and Breathing Controlled
NCT00097630
Lymphoma Follow-up
NCT00744120
Effects of Hormonal Infertility Treatment on Cognition in Pre-Menopausal Women
NCT00113867
The TLC2 (Teaching Healthy Lifestyles to Caregivers 2)/CALM (Counseling Advice for Lifestyle Management) Study
NCT00131105
Forearm Vascular Relaxation
NCT00182923
Risk Evaluation and Education for Alzheimer's Disease (REVEAL) II
NCT00089882
Early Markers of Cognitive Change and Alzheimer s Disease
NCT01867346
The Genetic Characterization of Dementia
NCT01867359
Early Markers of Alzheimer's Disease: Structural and Functional Brain Changes
NCT01867372
Analysis of Atropine and Propranolol Induced Changes
NCT00251602
Salt Study: Inhibited Breathing Pattern and Sodium Inhibitors in Sodium Sensitivity of Blood Pressure
NCT00800228
Screening Protocol to Evaluate Volunteers for NIA Approved Studies
NCT02091271
GIP: Glucose-dependent Insulinotropic Peptide
NCT00239707
Studies of Heritable Disorders of Connective Tissue
NCT00270686
VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)
NCT00056225
Osteoarthritis and Body Composition: Evaluation of Systematic Mediators
NCT00771082
Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study
NCT00053599
Dietary Energy Restriction and Metabolic Aging in Humans
NCT00183027
HORMA: Hormonal Regulators of Muscle and Metabolism in Aging
NCT00183040
MIRAGE: Multi-Institutional Research in Alzheimer's Genetic Epidemiology
NCT00239759
Effects of Dehydroepiandrosterone (DHEA) in Humans
NCT00182975
The Immune Function Intervention Trial
NCT00548990
Collection of Bone Marrow Aspirate From Volunteer Donors
NCT00183066
Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)
NCT00043849
CALERIE (Tufts) - Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy
NCT00099099
CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
NCT00099151
CALERIE (Washington University): Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy
NCT00099138
Race, Menopause and Metabolism After Exercise and Diet
NCT00882141
GRACE: Geriatric Resources for Assessment and Care of Elders
NCT00182962
Pioglitazone in Alzheimer Disease
NCT00982202
Testosterone Effects on Bone and Frailty
NCT00182871
Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification
NCT00183001
The HIP Impact Protection Program (HIP PRO)
NCT00058864
A Comparison of Weighted Vest Exercise and Strength Training
NCT00158119
Shingles: Immune Effects of Tai Chi
NCT00118885
Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans
NCT00099697
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 18 |
| Phase 2 | 20 |
| Phase 3 | 14 |
| Phase 4 | 4 |
Therapeutic Areas
What the Pipeline for National Institute on Aging (NIA) Shows
According to the ClinicalTrials.gov registry, National Institute on Aging (NIA) is linked to 131 US clinical trials across every stage of research activity. Of those, 12 studies are currently recruiting, about 9% of the sponsor's indexed portfolio, and 103 are already marked complete, representing roughly 79% of the total.
The phase mix for National Institute on Aging (NIA) reports 18 late-stage studies (Phase 3 and Phase 4 combined) and 38 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute on Aging (NIA) is Aging with 7 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.