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NCT01431677 · ClinicalTrials.gov registry record · NA
Muscle Biopsies in Healthy Volunteers
A NA study, sponsored by National Institute on Aging (NIA).
- Terminated
- Registry status
- NA
- Development phase
- 22
- Enrollment target
NCT01431677 is a NA study that was terminated before completion, run by National Institute on Aging (NIA). The registered enrollment target is 22 participants.
The verdict
NCT01431677, a NA study, was terminated before completion, sponsored by National Institute on Aging (NIA).
- TERMINATED
- Registry status
- NA
- Development phase
- 22 participants
- Enrollment target
Study Summary
Background: \- In individuals as they age, changes in muscle tissue can significantly affect their muscle strength and exercise endurance. This process, known as sarcopenia, may lead to decreased mobility and physical weakness, which is what we in general refer to as frailty. The causes of sarcopenia and why it affects some individuals more than others are not known, but many factors influence muscle physiology and function, including metabolic, hormonal, environmental, and lifestyle factors. Researchers interested in identifying factors involved in the start and progression of sarcopenia need of samples of human muscle tissue and cells for laboratory investigations. Objectives: * To train researchers in the appropriate procedures for performing muscle biopsies and collecting, labeling, and storing the samples. * Develop a data base of specific scientific studies evaluating the physiological and metabolic function of muscle that can be used in future studies. Eligibility: \- Healthy volunteers at least 18 years of age. Design: * Participants will be screened with a full medical history and physical examination, as well as blood and urine tests, and will schedule a date for the muscle biopsy. * Participants will have a muscle biopsy, with tissue and cells taken from the upper part of the thigh. A local anesthetic will be given for the procedure. Participants will also provide a blood sample and have an electrocardiogram to evaluate heart function. * Participants will have a followup visit 1 week after the biopsy visit to evaluate the healing process and provide any further treatment for the affected area, after which they may fully resume normal activities.
Interventions
- PROCEDURE Muscle Biopsy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2010-05-17 |
| Est. Completion | 2014-07-29 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01431677
The ClinicalTrials.gov registry entry for NCT01431677 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute on Aging (NIA), which has 131 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Muscle Biopsy is the first listed.
NCT01431677 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01431677 about?
NCT01431677 is a clinical study titled "Muscle Biopsies in Healthy Volunteers". Background: \- In individuals as they age, changes in muscle tissue can significantly affect their muscle strength and exercise endurance. This process, known as sarcopenia, may lead to decreased mobility and physical weakness, which is what we in general refer to as frailty. The causes of sarcopen...
What is the current status of trial NCT01431677?
This trial is currently terminated. It is a NA study. The enrollment target is 22 participants. The study started on 2010-05-17. Estimated completion is 2014-07-29.
What interventions are being tested in trial NCT01431677?
The interventions under investigation include: Muscle Biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT01431677?
This trial is sponsored by National Institute on Aging (NIA), which has 131 total clinical trials registered on ClinicalTrials.gov.
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