National Institute of Neurological Disorders and Stroke (NINDS)

567 total trials 48 currently recruiting 467 completed

National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.

Trial Pipeline

567 total, page 6 of 12

COMPLETED

Brain Excitability in Patients With Succinic Semialdehyde Dehydrogenase Deficiency

NCT00132366

COMPLETED Phase 1

Deep Brain Stimulation to Treat Cervical Dystonia

NCT00132340

COMPLETED

Mirroring a Movement

NCT00123448

COMPLETED

Neuropathology of Spasmodic Dysphonia

NCT00118586

COMPLETED

Interhemispheric Plasticity in Humans

NCT00120666

COMPLETED Phase 2

Double Blind Trial of DC Polarization in FTD

NCT00117858

COMPLETED

MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle

NCT00117221

COMPLETED

Motor Performance in Chronic Stroke Patients

NCT00110175

COMPLETED

Effects of Two Different Kinds of Exercise on Stroke Rehabilitation

NCT00108680

COMPLETED Phase 2

Talampanel to Treat Parkinson's Disease

NCT00108667

COMPLETED

Study to Collect Data on Fabry Disease Patients With Enhanceable Alpha-Galactosidase A Activity

NCT00106912

COMPLETED Phase 2

Transcranial Electrical Polarization to Treat Focal Hand Dystonia

NCT00106782

COMPLETED Phase 2

Deep Brain Stimulation for Cervical Dystonia

NCT00105430

COMPLETED

Genetic Characterization of Parkinson's Disease

NCT00105131

COMPLETED Phase 1

Nitrite Infusion in Healthy Volunteers

NCT00103025

COMPLETED

Effect of Surface Electrical Stimulation on Movement of the Larynx

NCT00104000

COMPLETED

Brain Function in Focal Dystonia

NCT00102999

COMPLETED Phase 2

Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tremor

NCT00102596

COMPLETED

Brain Reorganization Following Constraint-Induced Therapy in Children With Cerebral Palsy

NCT00100503

COMPLETED

Biomarkers in Multiple Sclerosis

NCT00325988

COMPLETED

Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis

NCT00099307

COMPLETED Phase 1

Safety Study of Interferon Beta 1a to for Acute Stroke

NCT00097318

COMPLETED

Brain Activities Associated With Different Facial Expressions Using Blood Oxygenation Level Dependent Functional MRI

NCT00096564

COMPLETED Phase 2

Non-Pharmacologic Therapy for Neurocardiogenic Syncope

NCT00096902

COMPLETED Phase 4

Replagal Enzyme Replacement Therapy for Adults With Fabry Disease

NCT00097890

COMPLETED

The Functional Anatomy of Personality Trait Knowledge: An fMRI Study

NCT00095407

COMPLETED Phase 2

Propranolol to Treat Fainting in Children With Sympathoadrenal Imbalance

NCT00093860

COMPLETED Phase 2

Effects of Lithium and Divalproex'on Brain-Derived Neurotrophic Factor in Huntington's Disease

NCT00095355

COMPLETED

Neural Correlates of Observation of Tactile Stimulation in Healthy Subjects

NCT00091533

COMPLETED Phase 2

Rituximab to Treat Stiff Person Syndrome

NCT00091897

COMPLETED Phase 2

Lisuride Patch to Treat Parkinson's Disease

NCT00089622

COMPLETED

Treatment Study of Frontotemporal Dementia

NCT00088751

COMPLETED Phase 3

Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumors

NCT00088400

COMPLETED Phase 2

Effect of Lithium and Divalproex in Alzheimer's Disease

NCT00088387

COMPLETED

Effect of Direct Current Polarization on Brain Function

NCT00088569

COMPLETED

Biological Markers in Parkinson's Disease

NCT00088335

COMPLETED Phase 2

ACP-103 to Treat Parkinson's Disease

NCT00086294

COMPLETED

Brain Electrical Stimulation to Enhance Recovery After Stroke

NCT00085657

COMPLETED

Herpes Virus-6 and Epilepsy

NCT00085683

COMPLETED

Observational Learning in Stroke Patients

NCT00083642

COMPLETED

Role of the Brain in Making Economic Decisions

NCT00083317

COMPLETED

Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives

NCT00082615

COMPLETED

Pelvic Pain in Women With Endometriosis

NCT00073801

COMPLETED

Language and Emotional Function in Patients With Temporal Lobe Epilepsy

NCT00081432

COMPLETED

Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder

NCT00081419

COMPLETED

Timing of Voluntary Movement in Patients With Schizophrenia

NCT00080548

COMPLETED

Brain Physiology in Polio Survivors

NCT00080600

COMPLETED

Rhythm Perception and Generation

NCT00080067

COMPLETED Phase 2

Octanol to Treat Essential Tremor

NCT00080366

COMPLETED Phase 2

Alemtuzumab to Treat Sporadic Inclusion Body Myositis

NCT00079768

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Phase Distribution

PhaseTrial count
Phase 1 80
Phase 2 78
Phase 3 11
Phase 4 5

What the Pipeline for National Institute of Neurological Disorders and Stroke (NINDS) Shows

According to the ClinicalTrials.gov registry, National Institute of Neurological Disorders and Stroke (NINDS) is linked to 567 US clinical trials across every stage of research activity. Of those, 48 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 467 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Neurological Disorders and Stroke (NINDS) reports 16 late-stage studies (Phase 3 and Phase 4 combined) and 158 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Neurological Disorders and Stroke (NINDS) is Healthy with 23 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.