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NCT00120666 · ClinicalTrials.gov registry record
Interhemispheric Plasticity in Humans
A clinical trial of Healthy, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 108
- Enrollment target
- 1
- Study location
NCT00120666: Completed study of Healthy, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00120666 is a study of Healthy that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 108 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00120666, a study of Healthy, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 108 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will determine how the brain controls movements by sending messages to the spinal cord and muscles. Researchers want to know if strengthening a hand muscle will increase the strength of the same muscle in the other hand, and if these changes happen in the brain or spine, or both. Plasticity in this study refers to the capacity for continuous changes of the neural pathways in the brain and nervous system. Researchers have seen cases in which using a muscle extensively (force production) in one muscle group has increased the strength of the same muscle group on the opposite side of the body (force transfer). This situation happens without the unused muscle becoming larger-suggesting that the practice causes changes in some parts of the brain or spine. It is vital for scientists to know how this effect works, so that they can create new rehabilitation methods for people who cannot move or who have difficulty moving one side of their body. Patients ages 18 to 60 who are in good health and who do not have a history of major conditions affecting the bones, joints or nervous system may be eligible for this study. Patients will undergo a medical examination. There will be 1 or 2 testing sessions, 20 training sessions, and 1 or 2 final testing sessions, with patients being asked to come to the laboratory for as few as 4 times (about 10 hours total) or for up to 25 visits (about 20 hours total). The investigator will indicate which of six different groups that a patient is selected for. During testing sessions, the strength of the pointer and little fingers in each hand will be determined through the use of very brief electrical pulses. There also will be transcranial magnetic stimulation (TMS) and 1 Hz TMS. The researchers will place one or two wire coils on the patient's scalp and make marks on the scalp which will be removed at the end of the session. During the TMS, a brief electrical current is passed through the coil, creating a magnetic pulse that stimulat
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2005-07-08 |
| Est. Completion | 2007-06-25 |
What the finished NCT00120666 record still lists
NCT00120666 is an observational study that tracks outcomes without assigning an intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 0 interventions.
NCT00120666 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00120666 about?
NCT00120666 is a clinical study titled "Interhemispheric Plasticity in Humans". This study will determine how the brain controls movements by sending messages to the spinal cord and muscles. Researchers want to know if strengthening a hand muscle will increase the strength of the same muscle in the other hand, and if these changes happen in the brain or spine, or both. Plastici...
What is the current status of trial NCT00120666?
This trial is currently completed. The enrollment target is 108 participants. The study started on 2005-07-08. Estimated completion is 2007-06-25.
What conditions does trial NCT00120666 study?
This clinical trial studies the following conditions: Healthy.
Who is sponsoring clinical trial NCT00120666?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00120666 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00120666's enrollment target sits among peer trials
108 204th of 1090 higher than 884 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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