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NCT00117221 · ClinicalTrials.gov registry record
MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle
A clinical trial of Sleep, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 56
- Enrollment target
- 1
- Study location
NCT00117221: Completed study of Sleep, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00117221 is a study of Sleep that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 56 participants, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00117221, a study of Sleep, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will investigate the spatio-temporal characteristics of brain activity during sleep. Functional magnetic resonance imaging (fMRI) studies have shown that in the absence of external stimuli, the brain continues to show spatial patterns of activity that resemble those during sensory and cognitive tasks. This phenomenon greatly affects the interpretation of neuroimaging studies based on positive emission tomography (PET) and fMRI, which rely on the contrast between brain activity during a task and activity during rest. In addition, resting state activity in itself may reveal information on the large-scale organization of neuronal networks and on functional abnormalities related to disease. Participants should represent a broad cross section of the healthy adult population. Any neurologically and psychiatrically healthy male or nonpregnant female between 18 and 65 years old may be eligible. Studies will be conducted in the In Vivo NMR Research Center. Concurrent electroencephalogram (EEG) and MRI studies will last between 1 and 2 hours. A typical study involves 15 minutes of anatomical MRI scanning followed by a 60-minute functional scan during which the subject relaxes with eyes closed and is encouraged to sleep while the fMRI/EEG are performed. Participants may be scanned 1 to 20 times. No more than 1 scan will be performed per day and no more than 20 scans will be performed within a year. During the last 5 to 10 minutes of the scan, the participant will open his or her eyes and actively participate in a visual stimulation or attention task. The participant's alertness will be measured by a behavioral (button-press) response. The visual stimuli (contrast reversing checkerboard displays, alternated with uniform grey fields) will be presented using the standard projection system available with the MRI scanner. The attention task will involve repeated visual presentation of groups of letters and digits; the participant will be asked about the correspondence
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2005-06-28 |
| Est. Completion | 2014-02-11 |
What the finished NCT00117221 record still lists
NCT00117221 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 4,166-participant average among 151 other Sleep trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Sleep appearing as the primary indexed condition, and to 0 interventions.
NCT00117221 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00117221 about?
NCT00117221 is a clinical study titled "MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle". This study will investigate the spatio-temporal characteristics of brain activity during sleep. Functional magnetic resonance imaging (fMRI) studies have shown that in the absence of external stimuli, the brain continues to show spatial patterns of activity that resemble those during sensory and cog...
What is the current status of trial NCT00117221?
This trial is currently completed. The enrollment target is 56 participants. The study started on 2005-06-28. Estimated completion is 2014-02-11.
What conditions does trial NCT00117221 study?
This clinical trial studies the following conditions: Sleep.
Who is sponsoring clinical trial NCT00117221?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00117221 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00117221's enrollment target sits among peer trials
56 96th of 151 higher than 56 of 151 other Sleep trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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