Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01974427 · ClinicalTrials.gov registry record

Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions

A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

Completed
Registry status
154
Enrollment target

NCT01974427: Completed study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

NCT01974427 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 154 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01974427 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

COMPLETED
Registry status
154 participants
Enrollment target

Study Summary

Objective: The goal of this protocol is to improve understanding scale-free brain activity and conscious vs. unconscious processing by performing small behavioral, electrophysiological, neuroimaging and brain stimulation pilot substudies. This research is expected to help develop techniques and hypotheses for future research on these topics. We will conduct: * Pilot Substudy: Pilot substudies are exploratory in nature, in order to develop enough information to generate a hypothesis. The criterion for transition to a new full protocol will be acquisition of sufficient information to generate a power analysis. There are no enrollment limitations for pilot substudies. * Hypothesis-Testing Substudy is defined as a study with a specific hypothesis to be tested that can be completed with a few healthy volunteers or patients. Hypothesis-testing substudies will undergo statistical and PIRC reviews after 6 subjects (if there is one group) or after 12 (6 per arm) if two groups are studied before additional subjects are recruited. In the event of subject dropout or unsuccessful recording, replacement will be recruited. Together, the P.I. and PIRC will decide whether to continue the hypothesis substudy with more subjects without an amendment or whether an amendment or new protocol would be necessary. A memo requesting a review of hypothesis-testing substudies for possible additional enrollment will be sent to PIRC and the statistical reviewer. The memo will be forwarded to the CNS IRB. * Technical development of new experimental paradigms and data analysis methods. This protocol includes only non-invasive techniques with minimal risk (MRI, EEG, MEG, EMG, tDCS). Study Population: We plan to recruit up to 120 healthy volunteers aged 18-65. Design: We will design small projects that are pertinent to the theme of scale-free brain activity and conscious/unconscious processing. We will investigate healthy volunteers in the resting state or while they perform simple motor or s

Trial Details

FieldValue
Enrollment Target 154 participants
Start Date 2013-10-26
Est. Completion 2018-06-20

What the finished NCT01974427 record still lists

NCT01974427 is an observational study that tracks outcomes without assigning an intervention. The registered 154 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 0 interventions.

NCT01974427 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01974427 about?

NCT01974427 is a clinical study titled "Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions". Objective: The goal of this protocol is to improve understanding scale-free brain activity and conscious vs. unconscious processing by performing small behavioral, electrophysiological, neuroimaging and brain stimulation pilot substudies. This research is expected to help develop techniques and hyp...

What is the current status of trial NCT01974427?

This trial is currently completed. The enrollment target is 154 participants. The study started on 2013-10-26. Estimated completion is 2018-06-20.

Who is sponsoring clinical trial NCT01974427?

This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04300998 · 154 participants

    Study of CAR-T Therapy in Older Patients

  • NCT04597372 · 154 participants · Phase 2

    Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery

  • NCT05294042 · 154 participants · NA

    Patient Navigators for Children's Community Mental Health Services in High Poverty Urban Communities

  • NCT05512390 · 154 participants · Phase 1

    A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT01974427, the US trial registry maintained by the National Library of Medicine. NCT01974427 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.