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NCT01200966 · ClinicalTrials.gov registry record
Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 96
- Enrollment target
NCT01200966 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 96 participants.
The verdict
NCT01200966 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 96 participants
- Enrollment target
Study Summary
Background: \- Essential tremor (ET) is a neurological disorder involving uncontrollable shaking, which over time can interfere with mobility and affect routine aspects of daily living. Several medications are used to treat ET, but these medications are often only partially effective and can have side effects. About two-thirds (66%) of people with ET have some relief from drinking alcohol, which suggests that alcohol affects the part of the brain causing the tremor. However, more research is needed to better understand the effects of alcohol or what areas of the brain might be important in the response. Objectives: * To study to what extent alcohol is reducing tremor in a group of patients with essential tremor. * To use transcranial magnetic stimulation to study the effects of alcohol on essential tremor. Eligibility: \- Individuals who are at least 21 years of age, have been diagnosed with essential tremor and have tremor in both hands, and can tolerate being off all medications for essential tremor for up to 4 weeks. Design: * This study has one screening visit (1 to 2 hours), followed by one study visit (3 to 5 hours). Participants might be asked to also take part in one additional study visit (3 to 5 hours). The maximum period between the study visits is 3 months. * Participants will be screened with a medical history, physical examination, and blood tests. At this visit, participants will receive information about how to safely taper off their current ET medications before the start of the study. * Participants must be willing to abstain from drinking any alcohol or caffeine (or consuming foods with caffeine such as chocolate) for at least 2 days before the study visits. Participants must also fast overnight (for at least 8 hours) before the study visits. * At the first study visit, participants will receive a single drink of alcohol (mixed with a noncaffeinated drink) and will complete movement tests to determine whether the alcohol improves the tremor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2010-08-30 |
| Est. Completion | 2017-01-04 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01200966
The ClinicalTrials.gov registry entry for NCT01200966 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01200966 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01200966 about?
NCT01200966 is a clinical study titled "Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates". Background: \- Essential tremor (ET) is a neurological disorder involving uncontrollable shaking, which over time can interfere with mobility and affect routine aspects of daily living. Several medications are used to treat ET, but these medications are often only partially effective and can have s...
What is the current status of trial NCT01200966?
This trial is currently completed. The enrollment target is 96 participants. The study started on 2010-08-30. Estimated completion is 2017-01-04.
Who is sponsoring clinical trial NCT01200966?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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