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NCT01375595 · ClinicalTrials.gov registry record

Brain Areas Involved in Sound and Spoken Word Memory

A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

Terminated
Registry status
45
Enrollment target

NCT01375595: Clinical Trial study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

NCT01375595 is a clinical trial that was terminated before completion, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 45 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01375595 was terminated before completion, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

TERMINATED
Registry status
45 participants
Enrollment target

Study Summary

Background: \- Studies have shown that animals such as monkeys and dogs have excellent sight and touch memory but perform poorly on sound memory tasks. Human brains have certain areas that are important for speaking and understanding language. These areas may be involved in sound and spoken word memory. Researchers want to study these areas of the brain to find out if the memory for sounds requires brain structures that are usually associated with language learning and are unique to humans. Objectives: \- To use magnetic resonance imaging to study areas of the brain involved in sound memory. Eligibility: \- Healthy right-handed volunteers between 18 and 50 years of age. They must be native English speakers and have completed high school. Design: * The study requires a screening visit and 1 or 2 study visits to the National Institutes of Health Clinical Center. * At the screening visit, volunteers will have a medical history taken. They will also have physical and neurological exams, and complete a questionnaire. Women of childbearing age will give a urine sample. Participants who have not had a magnetic resonance imaging (MRI) scan in the past year will have one at this visit. * At the second visit, participants will have tests of sound memory. They will listen to a set of nonsense words spoken through earphones and memorize the words. Then they will listen to the words again to judge if the words were part of the earlier list. Participants will have a 1 hour break, then do the sound memory test again. During the second test they will have repetitive transcranial magnetic stimulation (rTMS), which stimulates different regions of the brain. * If the group results from the testing sessions are positive, there will be a third visit. At this visit, participants will have a sound perception test. They will listen to words spoken through earphones and judge whether the words in the pair are the same or different. Participants will have rTMS during these tests as we

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2011-05-26
Est. Completion 2015-10-30

Why NCT01375595 stopped before completion

NCT01375595 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 45 participants, a relatively small participant target.

The record links to 0 conditions, and to 0 interventions.

NCT01375595 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01375595 about?

NCT01375595 is a clinical study titled "Brain Areas Involved in Sound and Spoken Word Memory". Background: \- Studies have shown that animals such as monkeys and dogs have excellent sight and touch memory but perform poorly on sound memory tasks. Human brains have certain areas that are important for speaking and understanding language. These areas may be involved in sound and spoken word me...

What is the current status of trial NCT01375595?

This trial is currently terminated. The enrollment target is 45 participants. The study started on 2011-05-26. Estimated completion is 2015-10-30.

Who is sponsoring clinical trial NCT01375595?

This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT01375595, the US trial registry maintained by the National Library of Medicine. NCT01375595 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.