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NCT01260740 · ClinicalTrials.gov registry record
The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Terminated
- Registry status
- 174
- Enrollment target
NCT01260740 is a clinical trial that was terminated before completion, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 174 participants.
The verdict
NCT01260740 was terminated before completion, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- TERMINATED
- Registry status
- 174 participants
- Enrollment target
Study Summary
Background: \- Two areas on the surface of the brain, the dorsolateral prefrontal cortex (DLPFC) and motor cortex (MC), play a key role during learning. Researchers are interested in determining the effect that transcranial magnetic stimulation (TMS) on the DLPFC and MC has on participants' performance of learning tasks. By studying the effect of TMS on reaction time, learning, and memory, researchers hope to better understand how to treat conditions such as Parkinson's disease and traumatic brain injury that affect these parts of the brain. Objectives: * To study the effects of transcranial magnetic stimulation on the dorsolateral prefrontal cortex and motor cortex. * To learn which areas of the brain are used to perform certain learning and memory tasks. Eligibility: \- Healthy, right-handed individuals between 18 and 70 years of age. Design: * Participants will be screened with a physical and neurological examination and a medical and psychiatric history. * Participants will be asked to take part in one of five different parts of this study. Most participants will have four 2-hour visits to the National Institutes of Health Clinical Center. Some participants (those involved in Part 5) will have only one 2-hour visit. * Parts 1 and 2 (four visits): Participants will have TMS, and then do a learning task that may provide a small monetary reward. On the first visit, before the TMS, participants will take an intelligence test based on reading aloud the words given on a card. Participants who have not had a routine magnetic resonance imaging (MRI) scan of the brain within the past year will also have a scan. * Parts 3 and 4 (four visits): Participants will have a functional MRI scan while doing a learning task that may provide a small monetary reward. On the first visit, before the functional MRI, participants will take an intelligence test based on reading aloud the words given on a card. Participants who have not had a routine magnetic resonance imaging (MRI)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 174 participants |
| Start Date | 2010-12-07 |
| Est. Completion | 2017-06-23 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01260740
The ClinicalTrials.gov registry entry for NCT01260740 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 174 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01260740 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01260740 about?
NCT01260740 is a clinical study titled "The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans". Background: \- Two areas on the surface of the brain, the dorsolateral prefrontal cortex (DLPFC) and motor cortex (MC), play a key role during learning. Researchers are interested in determining the effect that transcranial magnetic stimulation (TMS) on the DLPFC and MC has on participants' perform...
What is the current status of trial NCT01260740?
This trial is currently terminated. The enrollment target is 174 participants. The study started on 2010-12-07. Estimated completion is 2017-06-23.
Who is sponsoring clinical trial NCT01260740?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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