National Institute of Neurological Disorders and Stroke (NINDS)

567 total trials 48 currently recruiting 467 completed

National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.

Trial Pipeline

567 total, page 10 of 12

COMPLETED

Physiologic Studies of Spasticity

NCT00014976

COMPLETED Phase 2

Amlodipine Plus Botulinum Toxin for Focal Dystonia

NCT00015457

COMPLETED

Effects of Flumazenil on Brain Excitability

NCT00015678

COMPLETED

Magnetic Resonance Imaging to Investigate Silent Strokes During Neck and Skull Angioplasty

NCT00015717

COMPLETED Phase 2

Riluzole to Treat Parkinson's Disease

NCT00013624

TERMINATED Phase 2

E-Selectin Nasal Spray to Prevent Stroke Recurrence

NCT00012454

COMPLETED

Study and Surgical Treatment of Syringomyelia

NCT00011245

COMPLETED Phase 2

Rolipram to Treat Multiple Sclerosis

NCT00011375

COMPLETED Phase 2

EMD 128130 for the Treatment of Parkinson's Disease

NCT00009048

COMPLETED

Ketogenic Diet in Lafora Disease

NCT00007124

COMPLETED

Gluten-Free Diet in Patients With Gluten Sensitivity and Cerebellar Ataxia

NCT00006492

COMPLETED

Study of Brain Changes Shaped by Experience

NCT00006424

COMPLETED Phase 2

KW-6002 to Treat Parkinson's Disease

NCT00006337

COMPLETED

Hand Exercise and Upper Arm Anesthesia to Improvements Hand Function in Chronic Stroke Patients

NCT00006414

COMPLETED

Sensory Training to Treat Focal Dystonia

NCT00006336

COMPLETED Phase 2

Effects of Monoamine Reuptake Inhibitor NS2330 in Parkinson's Disease

NCT00006077

COMPLETED

Effect of Levetiracetam on Brain Excitability

NCT00006191

TERMINATED Phase 1

Brain Infusion of Muscimol to Treat Epilepsy

NCT00005925

COMPLETED Phase 2

Continuously Infused Recombinant-Methionyl Human Glial Cell Line-Derived Neurotrophic Factor (GDNF) to Treat Progressive Supranuclear Palsy

NCT00005903

COMPLETED

PET Scans in Normal Volunteers and Patients With Fabry Disease

NCT00005111

COMPLETED

Study of Brain Activity During Speech Production and Speech Perception

NCT00004991

COMPLETED NA

Electromyography to Diagnose Neuromuscular Disorders

NCT00004553

COMPLETED Phase 1

Gentamicin Treatment of Muscular Dystrophy

NCT00005574

COMPLETED Phase 3

Hypothermia During Intracranial Aneurysm Surgery Trial

NCT00029133

COMPLETED Phase 2

Study of LY300164 for the Treatment of Parkinson's Disease

NCT00004576

COMPLETED

Positron Emission Tomography (PET) to Study Brain Signaling

NCT00044200

COMPLETED Phase 1

1-Octanol to Treat Essential Tremor

NCT00001986

COMPLETED Phase 2

Brain Imaging and Retreatment Study of Persistent Lyme Disease

NCT00037479

COMPLETED

Blood Sampling for Neurochemical and Genetic Testing

NCT00001147

COMPLETED

Detecting Malignant Brain Tumor Cells in the Bloodstream During Surgery to Remove the Tumor

NCT00001148

COMPLETED Phase 2

Oxandrolone Compared With a Placebo on Growth Rate in Girls With Growth Hormone-Treated Turner's Syndrome

NCT00004275

COMPLETED

Electrical Muscle Stimulation to Aid Swallowing in Dysphagia

NCT00001936

COMPLETED Phase 2

Zenapax to Treat Multiple Sclerosis

NCT00001934

COMPLETED

Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes

NCT00004351

COMPLETED Phase 2

Nefiracetam in the Treatment of Alzheimer's Disease

NCT00001933

COMPLETED

Serotonin Receptors in Seizure Disorders

NCT00001932

COMPLETED Phase 2

Treatment of Parkinson's Disease With a Transdermal Skin Patch

NCT00001931

COMPLETED

The Connection Between Areas in the Brain of Blind Patients

NCT00001926

COMPLETED Phase 2

Treatment of Huntington's Chorea With Amantadine

NCT00001930

COMPLETED Phase 2

Treatment of Parkinson's Disease With Eliprodil

NCT00001929

COMPLETED

Intravenous Levodopa for the Diagnosis of Parkinson's Disease

NCT00001928

COMPLETED

Study of Abnormal Blood Clotting in Children With Stroke

NCT00001927

COMPLETED

Study of Attention Deficit/Hyperactivity Disorder Using Transcranial Magnetic Stimulation

NCT00001915

COMPLETED Phase 3

Reduced Manipulation of the Aorta and Neurobehavioral Outcome Trial

NCT00059319

COMPLETED Phase 3

Theory-Based Interventions for Smoking and Obesity (Challenge) Trial

NCT00040287

COMPLETED Phase 2

Effect of Alcohol on Tremors

NCT00001925

COMPLETED Phase 1

Transcranial Magnetic Stimulation for the Treatment of Phantom Pain

NCT00001923

COMPLETED

Sensory Function in Idiopathic Voice Disorders

NCT00001922

COMPLETED Phase 2

Efficacy of a Family Telephone Intervention for Stroke

NCT00031265

COMPLETED Phase 2

Parkinson's Disease Treatment With Coenzyme Q10

NCT00004731

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Phase Distribution

PhaseTrial count
Phase 1 80
Phase 2 78
Phase 3 11
Phase 4 5

What the Pipeline for National Institute of Neurological Disorders and Stroke (NINDS) Shows

According to the ClinicalTrials.gov registry, National Institute of Neurological Disorders and Stroke (NINDS) is linked to 567 US clinical trials across every stage of research activity. Of those, 48 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 467 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Neurological Disorders and Stroke (NINDS) reports 16 late-stage studies (Phase 3 and Phase 4 combined) and 158 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Neurological Disorders and Stroke (NINDS) is Healthy with 23 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.