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NCT00037479 · ClinicalTrials.gov registry record · Phase 2

Brain Imaging and Retreatment Study of Persistent Lyme Disease

A Phase 2 study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

Completed
Registry status
Phase 2
Development phase
65
Enrollment target

NCT00037479: Completed Phase 2 study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

NCT00037479 is a Phase 2 study that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 65 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (51% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00037479, a Phase 2 study, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

COMPLETED
Registry status
Phase 2
Development phase
65 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether patients with persistent memory problems after Lyme disease benefit from an additional longer course of IV antibiotic therapy; to use modern brain imaging technology to determine whether the problem in the central nervous system is primarily one of poor blood flow or one of impaired nerve cell functioning; and to try to identify biological markers prior to treatment that will identify patients who are more or less likely to respond to the study treatment.

Interventions

  • DRUG ceftriaxone

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 1999-12
Phase Phase 2

What the finished NCT00037479 record still lists

NCT00037479 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (51% lower).

The record links to 0 conditions, and to 1 intervention - of which ceftriaxone is the first listed.

NCT00037479 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00037479 about?

NCT00037479 is a clinical study titled "Brain Imaging and Retreatment Study of Persistent Lyme Disease". The purpose of this study is to determine whether patients with persistent memory problems after Lyme disease benefit from an additional longer course of IV antibiotic therapy; to use modern brain imaging technology to determine whether the problem in the central nervous system is primarily one of p...

What is the current status of trial NCT00037479?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 65 participants. The study started on 1999-12.

What interventions are being tested in trial NCT00037479?

The interventions under investigation include: ceftriaxone (DRUG).

Who is sponsoring clinical trial NCT00037479?

This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00037479's enrollment target sits among peer trials

65 987th of 2000 higher than 1,005 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00037479, the US trial registry maintained by the National Library of Medicine. NCT00037479 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.