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NCT00001927 · ClinicalTrials.gov registry record
Study of Abnormal Blood Clotting in Children With Stroke
A clinical trial of Cerebrovascular Accident and Vascular Disease, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 130
- Enrollment target
- 1
- Study location
NCT00001927 is a study of Cerebrovascular Accident and Vascular Disease that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 130 participants, below the 513-participant average among 26 other Cerebrovascular Accident trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00001927, a study of Cerebrovascular Accident and Vascular Disease, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
Effective treatment and prevention strategies for childhood stroke and porencephaly can only be developed once the causes are understood. There is increasing evidence that inherited and acquired coagulation abnormalities alone or in combination with environmental factors, predispose to arterial and venous thrombosis. Inherited abnormalities of factor V Leiden, prothrombin, protein C, protein S, and antithrombin III may account for many of these thromboses. At present there is little information on the existing distribution of these coagulation anomalies in children with thrombosis. Recent reports also suggest that these clotting abnormalities may be responsible for some instances of intracranial hemorrhage, porencephaly, cerebral palsy and fetal death. This study will measure the frequency of several coagulation factor abnormalities (factor V Leiden, prothrombin 20210A, protein C, protein S, antithrombin III, and antiphospholipid antibodies) in children with a history of porencephaly and stroke, and will compare these to the prevalence of these mutations in population controls and family members. We will also describe the exogenous conditions which in concert with these coagulation factors, may have led to the development of thrombosis in these children....
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 1999-02-22 |
| Est. Completion | 2011-05-04 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00001927
The ClinicalTrials.gov registry entry for NCT00001927 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 513-participant average among 26 other Cerebrovascular Accident trials with a reported enrollment target (75% lower). The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Cerebrovascular Accident appearing as the primary indexed condition, and to 0 interventions.
NCT00001927 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00001927 about?
NCT00001927 is a clinical study titled "Study of Abnormal Blood Clotting in Children With Stroke". Effective treatment and prevention strategies for childhood stroke and porencephaly can only be developed once the causes are understood. There is increasing evidence that inherited and acquired coagulation abnormalities alone or in combination with environmental factors, predispose to arterial and ...
What is the current status of trial NCT00001927?
This trial is currently completed. The enrollment target is 130 participants. The study started on 1999-02-22. Estimated completion is 2011-05-04.
What conditions does trial NCT00001927 study?
This clinical trial studies the following conditions: Cerebrovascular Accident, Vascular Disease, Brain Disease, Blood Coagulation Disorder, Abnormalities.
Who is sponsoring clinical trial NCT00001927?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001927 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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