National Institute of Neurological Disorders and Stroke (NINDS)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Neurological Disorders and Stroke (NINDS) sits in the top decile of US sponsors by registered trial count (#61 of 15,742 sponsors by registered trial count).

567 total trials 48 currently recruiting 467 completed early-phase tilt top decile by trial count

National Institute of Neurological Disorders and Stroke (NINDS): 567 sponsored US clinical trials, 48 recruiting.

National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.

Top-decile sponsor footprint

National Institute of Neurological Disorders and Stroke (NINDS) ranks in the top decile of sponsors by registered trial count (#61 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 70/100

467 of 508 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

567 total, page 9 of 12

COMPLETED

The Role of Dopamine in Motor Learning in Healthy Subjects and Patients With Parkinson's Disease

NCT00032812

COMPLETED Phase 2

ReoPro and Retavase to Restore Brain Blood Flow After Stroke

NCT00039832

TERMINATED

Brain Anatomy in Dystonia

NCT00031369

COMPLETED

GABA Levels in the Brains of Blind People

NCT00357409

COMPLETED

Cause, Development, and Progression of Stiff-Person Syndrome

NCT00030940

COMPLETED

Magnetic Resonance Spectroscopy to Evaluate Tourette s Syndrome

NCT00030953

COMPLETED

Immune Abnormalities in Sporadic Inclusion Body Myositis

NCT00030212

COMPLETED

Brain Control of Blinking

NCT00030199

COMPLETED Phase 4

Donepezil to Treat Dementia in Parkinson's Disease

NCT00030979

COMPLETED

Imaging Study of Automatic Movements

NCT00031382

COMPLETED

Brain Activity During Production of Movement

NCT00029939

COMPLETED

Interhemispheric Interactions Associated With Performance of Voluntary Movements in Patients With Stroke Motor Disability

NCT00029718

COMPLETED

Surround Inhibition in Patients With Dystonia

NCT00029601

COMPLETED

Effect of Transcranial Magnetic Stimulation on Free Will

NCT00029653

COMPLETED

Data Collection in Women With Fabry Disease

NCT00030134

COMPLETED Phase 2

Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease

NCT00029666

COMPLETED

Role of Brain Region Changes in Tactile (Touch) Ability Following Nerve Block

NCT00357058

COMPLETED

Brain Control of Bimanual (Both Hands) Movements

NCT00029302

COMPLETED

Comparison of Externally and Self-Initiated Movements

NCT00028197

COMPLETED NA

Enhancement of Use-Dependent Plasticity by Somatosensory Stimulation in Chronic Stroke

NCT00028379

COMPLETED

Enhanced Tactile (Touch) Spatial Acuity in Upper Limb Amputees

NCT00028210

COMPLETED

Role of the Intact Hemisphere in Recovery of Motor Function After Stroke

NCT00028184

COMPLETED Phase 1

Temperature Response to a Head-Neck Cooling System

NCT00025987

COMPLETED

Brain Activation in Vocal and Motor Tics

NCT00026000

COMPLETED

Study of Specimens Obtained During Epilepsy Surgery

NCT00025714

COMPLETED

EEG and EMG Studies of Hand Dystonia

NCT00025701

COMPLETED

Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex

NCT00024908

COMPLETED

EEG and EMG Analysis of Ideomotor Apraxia

NCT00024999

COMPLETED

Effect of Stimulus Rate on Cognitive and Motor Activity in Young Subjects, Elderly Subjects, and Patients With Parkinson's Disease

NCT00026598

COMPLETED

Electrical Stimulation to Improve Hand Function in Patients With Chronic Stroke

NCT00023569

COMPLETED

Eye-Hand Coordination in Children With Spastic Diplegia

NCT00024791

COMPLETED

Transcranial Magnetic Stimulation in Parkinson's Disease

NCT00023062

COMPLETED

Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis

NCT00023075

COMPLETED Phase 2

Motor Training to Treat Hand Dystonia

NCT00021853

COMPLETED

Motor Learning in Stroke Patients and Healthy Volunteers

NCT00021710

COMPLETED

Genetic Analysis of the Chiari I Malformation

NCT00004738

COMPLETED

Phenotype/Genotype Correlations in Neuromuscular Disorders

NCT00017745

COMPLETED

Transcranial Magnetic Stimulation (TMS) Studies of Dystonia

NCT00017875

COMPLETED

Study of Brain Control of Movement

NCT00017979

COMPLETED

Brain Excitability During Self-Paced Voluntary Movements

NCT00017966

COMPLETED

Cause and Pathogenesis of Neurometabolic Disorders

NCT00016562

COMPLETED

Screening and Natural History: Primary Lateral Sclerosis and Related Disorders

NCT00015444

TERMINATED

Evaluation and Treatment of Patients With Epilepsy

NCT00013845

COMPLETED

Language Stimuli Screening in Children

NCT00016796

COMPLETED Phase 1

Safety Study of Idebenone to Treat Friedreich's Ataxia

NCT00015808

COMPLETED

Differences in Brain Processing of First and Second Languages (Korean and English)

NCT00016510

COMPLETED Phase 1

1-Octanol to Treat Essential Tremor

NCT00016679

COMPLETED Phase 1

Study of Air Stream in Voice Production

NCT00015795

COMPLETED

The Natural History and Pathogenesis of Mucolipidosis Type IV

NCT00015782

COMPLETED

Diagnostic Evaluation of Patients With Neuromuscular Disease

NCT00015470

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Phase Distribution

PhaseTrial count
Phase 1 80
Phase 2 78
Phase 3 11
Phase 4 5

What is open in the National Institute of Neurological Disorders and Stroke (NINDS) pipeline

48 recruiting of 567 indexed (8% open); 467 completed (82%).

Phase mix: 16 late (III/IV) vs 158 early (I/II) (early-phase heavy).

Top condition: Healthy (23 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Neurological Disorders and Stroke (NINDS): open-pipeline peers nationwide

Peers matched on 567 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Neurological Disorders and Stroke (NINDS) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share National Institute of Neurological Disorders and Stroke (NINDS)Children's Hospital Medical Center, CincinnatiUniversity of Maryland, BaltimoreAmgenMerck Sharp & DohmeNational Jewish HealthACADIA PharmaceuticalsTexas Tech University Health Sciences Center, El PasoBoehringer Ingelheim
National Institute of Neurological Disorders and Stroke (NINDS) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Neurological Disorders and Stroke (NINDS) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 567 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Neurological Disorders and Stroke (NINDS) page

567 registered trials is a research-attention snapshot, not an endorsement of National Institute of Neurological Disorders and Stroke (NINDS) or any single study.

  • 48 of National Institute of Neurological Disorders and Stroke (NINDS)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition National Institute of Neurological Disorders and Stroke (NINDS) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Neurological Disorders and Stroke (NINDS) pipeline card: 567 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.