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NCT00006424 · ClinicalTrials.gov registry record
Study of Brain Changes Shaped by Experience
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 153
- Enrollment target
NCT00006424: Completed study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00006424 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 153 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00006424 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 153 participants
- Enrollment target
Study Summary
This study will use magnetic resonance imaging (MRI) scans to explore how the brain changes (reorganizes itself) in response to learning and to brain lesions in healthy people and people with various physical disabilities. Normal volunteers and patients with disabilities including blindness, limb amputation, hemispherectomy (removal of a cerebral hemisphere), and stroke may be eligible for this study. Candidates will be screened with medical and neurological examinations. Participants will have MRI scans while they lie still or perform certain movements, as instructed. MRI uses a strong magnetic field and radio waves instead of X-rays to show structural and chemical changes in tissues. During the scan, the subject lies on a table in a narrow cylinder containing a magnetic field. He or she can speak with a staff member through an intercom system at all times during the procedure. All participants will first have a scan to show brain structure, which will take about 30 minutes. A second scan will measure blood flow or biochemical concentration and will take from 1 to 2 1/2 hours. Depending on their disability, patients will participate in one of the following tests: * Blindness-This will study the ability of blind people to process tactile information. * Stroke- This will study mechanisms underlying recovery of motor function after stroke. The patient will perform voluntary movements or remain still during the scan. * Amputation- This will study mechanisms underlying the ability of the brain to reorganize after amputation. The patient will move different parts of the body or remain still during the scan. * Hemispherectomy- This will study mechanisms underlying the ability of one side of the brain to control movements of both arms. The patient will make different kinds of movements during the scan. Normal volunteers will participate in one of the following tests: * Use-dependent plasticity- This will evaluate the effectiveness of amphetamine and placebo in demons
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 153 participants |
| Start Date | 2000-10 |
| Est. Completion | 2002-01 |
What the finished NCT00006424 record still lists
NCT00006424 is an observational study that tracks outcomes without assigning an intervention. The registered 153 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00006424 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00006424 about?
NCT00006424 is a clinical study titled "Study of Brain Changes Shaped by Experience". This study will use magnetic resonance imaging (MRI) scans to explore how the brain changes (reorganizes itself) in response to learning and to brain lesions in healthy people and people with various physical disabilities. Normal volunteers and patients with disabilities including blindness, limb a...
What is the current status of trial NCT00006424?
This trial is currently completed. The enrollment target is 153 participants. The study started on 2000-10. Estimated completion is 2002-01.
Who is sponsoring clinical trial NCT00006424?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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