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NCT00059319 · ClinicalTrials.gov registry record · Phase 3
Reduced Manipulation of the Aorta and Neurobehavioral Outcome Trial
A Phase 3 study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- Phase 3
- Development phase
- 300
- Enrollment target
NCT00059319: Completed Phase 3 study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00059319 is a Phase 3 study that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 300 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (61% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00059319, a Phase 3 study, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 300 participants
- Enrollment target
Study Summary
The purpose of this trial is to determine whether aortic manipulation in patients undergoing coronary bypass graft surgery leads to increased incidence of microemboli and subsequent impairment of neurobehavioral function.
Interventions
- PROCEDURE single aorta clamp with retrograde cardioplegia
- PROCEDURE multiple aorta clamps with antegrade cardioplegia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 1999-01 |
| Phase | Phase 3 |
What the finished NCT00059319 record still lists
NCT00059319 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (61% lower).
The record links to 0 conditions, and to 2 interventions - of which single aorta clamp with retrograde cardioplegia is the first listed.
NCT00059319 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00059319 about?
NCT00059319 is a clinical study titled "Reduced Manipulation of the Aorta and Neurobehavioral Outcome Trial". The purpose of this trial is to determine whether aortic manipulation in patients undergoing coronary bypass graft surgery leads to increased incidence of microemboli and subsequent impairment of neurobehavioral function.
What is the current status of trial NCT00059319?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 300 participants. The study started on 1999-01.
What interventions are being tested in trial NCT00059319?
The interventions under investigation include: single aorta clamp with retrograde cardioplegia (PROCEDURE), multiple aorta clamps with antegrade cardioplegia (PROCEDURE).
Who is sponsoring clinical trial NCT00059319?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00059319's enrollment target sits among peer trials
300 1122nd of 2000 higher than 840 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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