National Heart, Lung, and Blood Institute (NHLBI)
National Heart, Lung, and Blood Institute (NHLBI) sponsors 501 registered US clinical trials on ClinicalTrials.gov, 62 of them currently recruiting, and 381 completed. 33 of these trials are in Phase 3-4 (later-stage) and 205 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atherosclerosis, with 12 trials.
Trial Pipeline
501 total, page 6 of 11
Effectiveness of Etanercept for Idiopathic Pneumonia Syndrome Following Stem Cell Transplantation (BMT CTN 0403)
NCT00421174
Drug Study of Albuterol to Treat Acute Lung Injury
NCT00434993
Establishing a Repository of Blood and DNA Samples From People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Genotype-Phenotype Database and Sample Repository)
NCT00528203
Niacin to Improve Blood Flow in People With Sickle Cell Disease
NCT00508989
Genes Causing Ebstein's Anomaly
NCT00497705
Pulmonary Hypertension, Hypoxia and Sickle Cell Disease
NCT00495638
Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers
NCT00488592
Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease
NCT00492531
Imaging of Totally Blocked Arteries
NCT00459446
Stem Cell Transplantation for Patients With Cancers of the Blood
NCT00467961
Effectiveness of an Anger and Stress Management Program on Reducing Blood Pressure Levels in Youth
NCT00508612
Model System for Transient Forearm Blood Vessel Dysfunction
NCT00453531
Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease Risk
NCT00613158
Wilm's Tumor 1 (WT1) Peptide Vaccine for High Risk Hematologic Malignancy
NCT00433745
Role of p53 Gene in Metabolism Regulation in Patients With Li-Fraumeni Syndrome
NCT00406445
Collection of Heart Tissue Sample During Open Heart Surgery
NCT00423553
Validation of MRI Measurement of Cardiac Blood Flow
NCT00417625
Rilonacept to Improve Artery Function in Patients With Atherosclerosis
NCT00417417
Dexamethasone to Prevent Oral Chronic Graft-versus-Host Disease
NCT00391170
Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease
NCT00368446
Alemtuzumab (Campath) to Treat T-Large Granular Lymphocyte Leukemia
NCT00345345
Catheter-Based Treatment of Cardiovascular Disease
NCT00380016
Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases
NCT00366509
Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants
NCT00378534
Lower But More Frequent Dose Rituximab to Treat Chronic Lymphocytic Leukemia
NCT00366418
Predicting Response to Cardiac Resynchronization Therapy in Heart Failure
NCT00359372
Cardiovascular Magnetic Resonance Imaging of Pediatric Normal Volunteers
NCT00353899
Cardiopulmonary Function Assessment and NO-Based Therapies for Patients With Hemolysis-Associated Pulmonary Hypertension
NCT00352430
Genetic and Nutritional Causes of Heart Birth Defects
NCT00368732
The Link Between Anemia and Deficits in Memory and Attention in Individuals With Sickle Cell Disease
NCT00451919
Lifetime Risk for Cardiovascular Disease Among Non-White Ethnic Groups
NCT00377702
An Evaluation of Safety and Efficacy of Escalating Doses of AMD3100 to Mobilize CD34+ Cells in Healthy Volunteers
NCT00322127
Telomere Repair Gene Mutation in Inflammatory Bowel Disease
NCT00353639
Sildenafil to Treat HIV-Associated Pulmonary Hypertension
NCT00327080
Endothelial Progenitor Cells and Nitric Oxide in Cardiac Rehabilitation Program Participants
NCT00308633
Childhood Asthma Research and Education (CARE) Network Trial - Montelukast or Azithromycin for Reduction of Inhaled Corticosteroids in Childhood Asthma (MARS)
NCT00471809
Atorvastatin to Treat Pulmonary Sarcoidosis
NCT00279708
Safety of Peptide Vaccination for Patients With Myelodysplastic Syndrome
NCT00270452
Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia
NCT00270478
Rituxan/BEAM vs Bexxar/BEAM in Autologous Hematopoietic Stem Cell Transplant for Non-Hodgkin's Lymphoma (BMTCTN0401)
NCT00329030
Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia
NCT00260689
The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress
NCT00250185
Effect of Regular Exercise on Vascular Function and Cardiovascular Risk in a Sedentary Work Force
NCT00246883
Alemtuzumab to Treat Severe Aplastic Anemia
NCT00195624
Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302)
NCT00224874
Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia
NCT00229619
Genomics of In-Stent Restenosis
NCT00341562
Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria
NCT00130000
A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome
NCT00217594
Acute Myeloid Leukemia T Cell Depletion to Improve Transplants in Adults With Acute Myeloid Leukemia (BMT CTN 0303)
NCT00201240
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 87 |
| Phase 2 | 118 |
| Phase 3 | 29 |
| Phase 4 | 4 |
Therapeutic Areas
What the Pipeline for National Heart, Lung, and Blood Institute (NHLBI) Shows
According to the ClinicalTrials.gov registry, National Heart, Lung, and Blood Institute (NHLBI) is linked to 501 US clinical trials across every stage of research activity. Of those, 62 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 381 are already marked complete, representing roughly 76% of the total.
The phase mix for National Heart, Lung, and Blood Institute (NHLBI) reports 33 late-stage studies (Phase 3 and Phase 4 combined) and 205 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Heart, Lung, and Blood Institute (NHLBI) is Atherosclerosis with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.