National Heart, Lung, and Blood Institute (NHLBI)
National Heart, Lung, and Blood Institute (NHLBI) sponsors 501 registered US clinical trials on ClinicalTrials.gov, 62 of them currently recruiting, and 381 completed. 33 of these trials are in Phase 3-4 (later-stage) and 205 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atherosclerosis, with 12 trials.
Trial Pipeline
501 total, page 5 of 11
A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia
NCT01187017
Effects of Rosuvastatin on the Immune System in Healthy Volunteers With Normal Cholesterol
NCT01200836
Ofatumumab-based Induction Chemoimmunotherapy in Previously Untreated Patients With CLL/SLL
NCT01145209
A Study of the Kinetics of Lymphoid Cells in Patients With Monoclonal B-cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL), Mantle Cell Lymphoma (MCL) and Healthy Volunteers
NCT01117142
Gardasil Vaccination in Post Stem Cell Transplant Patients
NCT01092195
Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702)
NCT01109004
Evaluation of Oral Alpha-Cyclodextrin for Decreasing Serum Cholesterol
NCT01131299
New Techniques to Evaluate Mitral Regurgitation
NCT01063322
Statins for Acutely Injured Lungs From Sepsis
NCT00979121
Cardiac MRI for Patients Enrolled in INFUSE-AMI
NCT01059214
Novel Influenza A (H1N1) Surveillance Registry
NCT01046331
Characterization of the Innate Immune Response in Healthy NIH Employees at Baseline and After Immunization With the H1N1 Vaccine
NCT00995527
A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma
NCT00994175
Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees atBaseline, and After Immunization With the H1N1 or Seasonal Influenza Vaccines
NCT01191853
Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies
NCT00995891
Clarification of Optimal Anticoagulation Through Genetics
NCT00839657
Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA Treatment
NCT00944749
Screening Protocol for Subjects Being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols
NCT00968084
X-ray Fluoroscopy Fused With Computed Tomography (XFC) Technical Development
NCT00965679
Comparison of Cardiac Computed Tomography and Vasodilator Stress Magnetic Resonance Imaging Perfusion in Patients With Prior Equivocal Stress Test for Detection of Coronary Artery Disease
NCT00929227
A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients
NCT00922883
A Pilot Study of the Safety and Activity of Escalating Doses of ON 01910.Na in Patients With Relapsed Mantle Cell Lymphoma, Multiple Myeloma, Chronic Lymphocytic Leukemia, and Related Lymphoid Malignancies
NCT00861510
Mismatched Donor Lymphocyte Infusions for Relapsed Disease Following Allogeneic Stem Cell Transplantation
NCT00859586
Pilot Study of Mitochondrial Biology in Human Platelets
NCT00833846
Long-term Oxygen Treatment Trial
NCT00692198
Collection of Blood and Bone Marrow Samples From Select Patients With CML to Measure Minimal Residual Disease
NCT00819143
Improving Neurologic Outcomes in People With Diabetes Who Are Undergoing Heart Surgery
NCT00836329
Neuropsychological Effects of Immunosuppressive Treatment in Subjects With Aplastic Anemia
NCT00767650
Identification of Risk Factors for Arrhythmia in Children and Adolescents With Hypertrophic Cardiomyopathy
NCT00753233
Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study)
NCT00890396
Multisystemic Therapy to Reduce Health Disparities in Adolescents With Asthma
NCT00916240
Natural Killer Cells and Bortezomib to Treat Cancer
NCT00720785
Transfusion-Associated Microchimerism in Previously Injured Individuals Who Received a Blood Transfusion
NCT00441779
Technical Development of Interventional Cardiovascular Magnetic Resonance Imaging in Normal Volunteers
NCT00720460
Screening for Subjects to Participate in Studies of Blood Disorders
NCT00695123
Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelodysplastic Syndrome
NCT00604201
Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women
NCT00666172
Evaluation of Toxicity From Stem Cell Transplant
NCT00631787
Biomarkers in Exhaled Breath From Asthmatic Patients
NCT00635271
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
NCT00011648
Cardiovascular Disease Screening
NCT00483951
Pilot Study to Assess the Proteome in Human Atrial Tissue
NCT00591903
Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study)
NCT00883948
Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study)
NCT00609180
Relation of White Blood Cell Function to Diabetes
NCT00570154
National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions
NCT01322165
Effect of Fasting on the Size of Abdominal Lymphatic Tumors in Women
NCT00552955
Safety of ON 01910.Na in Patients With Myelodysplasia
NCT00533416
Longitudinal Studies of HIV-Associated Lung Infections and Complications (Lung HIV)
NCT00933595
Association Between Abdominal Body Composition, Inflammation, and Risk for Cardiovascular Disease (The MESA ABD Study)
NCT00612365
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 87 |
| Phase 2 | 118 |
| Phase 3 | 29 |
| Phase 4 | 4 |
Therapeutic Areas
What the Pipeline for National Heart, Lung, and Blood Institute (NHLBI) Shows
According to the ClinicalTrials.gov registry, National Heart, Lung, and Blood Institute (NHLBI) is linked to 501 US clinical trials across every stage of research activity. Of those, 62 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 381 are already marked complete, representing roughly 76% of the total.
The phase mix for National Heart, Lung, and Blood Institute (NHLBI) reports 33 late-stage studies (Phase 3 and Phase 4 combined) and 205 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Heart, Lung, and Blood Institute (NHLBI) is Atherosclerosis with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.