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NCT00929227 · ClinicalTrials.gov registry record
Comparison of Cardiac Computed Tomography and Vasodilator Stress Magnetic Resonance Imaging Perfusion in Patients With Prior Equivocal Stress Test for Detection of Coronary Artery Disease
A clinical trial, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Completed
- Registry status
- 109
- Enrollment target
NCT00929227: Completed study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT00929227 is a clinical trial that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 109 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00929227 has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- COMPLETED
- Registry status
- 109 participants
- Enrollment target
Study Summary
Background: * Noninvasive cardiac stress testing is imperfect. Inconclusive test results generate further expensive testing. * In patients with known or suspected coronary artery disease, both computed tomography (CT) and magnetic resonance imaging (MRI) have been shown to provide suitable results for detecting the disease. However, both types of scans have limitations in their usefulness, and it is not known whether one is preferable in either accuracy or cost-effectiveness. Objectives: \- To determine the accuracy and cost-effectiveness of CT and MRI in subjects with a prior inconclusive heart stress test. Eligibility: \- Patients 18 years of age and older who have had an inconclusive heart stress test within the past 90 days. Design: * A blood test will be obtained prior to both heart tests. This will require less than a teaspoon of blood. * A CT scan will be performed, accompanied by beta blocker medications (to slow heart rate) or nitroglycerin (to enlarge blood vessels) to improve picture quality, as needed. * An MRI scan will be performed. Scans will be taken before, during, and after the patient receives vasodilators (to increase blood flow to the coronary arteries and detect blockages in heart blood vessels). * Heart rate and function will be monitored with an electrocardiogram.
Primary Outcome
estimate the sensitivity, specificity, and accuracy of MRI and CT, for detecting obstructive CAD in patients with a prior equivocal stress study
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 109 participants |
| Start Date | 2009-07-01 |
| Est. Completion | 2020-11-19 |
What the finished NCT00929227 record still lists
NCT00929227 is an observational study that tracks outcomes without assigning an intervention. The registered 109 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00929227 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00929227 about?
NCT00929227 is a clinical study titled "Comparison of Cardiac Computed Tomography and Vasodilator Stress Magnetic Resonance Imaging Perfusion in Patients With Prior Equivocal Stress Test for Detection of Coronary Artery Disease". Background: * Noninvasive cardiac stress testing is imperfect. Inconclusive test results generate further expensive testing. * In patients with known or suspected coronary artery disease, both computed tomography (CT) and magnetic resonance imaging (MRI) have been shown to provide suitable results ...
What is the current status of trial NCT00929227?
This trial is currently completed. The enrollment target is 109 participants. The study started on 2009-07-01. Estimated completion is 2020-11-19.
Who is sponsoring clinical trial NCT00929227?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
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