Mclean Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mclean Hospital sits in the top decile of US sponsors by registered trial count (#201 of 15,742 sponsors by registered trial count).

140 total trials 26 currently recruiting 92 completed early-phase tilt top decile by trial count

Mclean Hospital: 140 sponsored US clinical trials, 26 recruiting.

Mclean Hospital sponsors 140 registered US clinical trials on ClinicalTrials.gov, 26 of them currently recruiting, and 92 completed. 13 of these trials are in Phase 3-4 (later-stage) and 40 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Major Depressive Disorder, with 9 trials.

Top-decile sponsor footprint

Mclean Hospital ranks in the top decile of sponsors by registered trial count (#201 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

92 of 110 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

140 total, page 3 of 3

COMPLETED Phase 4

Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder.

NCT01148979

COMPLETED NA

Acute Glycine Pharmacodynamic Study

NCT01610011

COMPLETED Phase 2

Nabilone for Cannabis Dependence: A Pilot Study

NCT01347762

COMPLETED Phase 2

Kudzu Treatment for Alcohol Abuse

NCT01596231

COMPLETED Early Phase 1

Proton MRS Study of SSRI-Zolpidem Interactions

NCT01809626

COMPLETED Phase 1

Treatment Resistant Geriatric Depression in Primary Care

NCT01392287

COMPLETED NA

The Effects of Cranial Electrotherapy Stimulation (CES) on Brain Function, Brain Chemistry and Mood

NCT01860677

TERMINATED

Frovatriptan and Menstrual Migraine

NCT01114711

TERMINATED

Treximet Migraine Brain Imaging Research Study

NCT01112553

TERMINATED NA

Generalized Anxiety and Seroquel

NCT01066143

COMPLETED NA

An Open Label Trial of Memantine in the Treatment of Bulimia Nervosa and Body Dysmorphic Disorder

NCT01038128

COMPLETED Phase 2

Effects of Citicoline on Brain Function and Behavior in Marijuana-Dependent Individuals

NCT00158249

COMPLETED Phase 2

Cognitive Behavioral Therapy and the Nicotine Transdermal Patch for Cannabis Dependence and Nicotine Dependence

NCT01292642

COMPLETED Phase 2

Puerarin Effects on Alcohol Drinking

NCT00854724

COMPLETED NA

A Trial of SAMe for Treatment-Resistant Bipolar Depression

NCT00762268

COMPLETED NA

Women's Recovery Group (WRG) Study - A Randomized Controlled Stage II Trial

NCT01318538

COMPLETED Phase 2

The Use of a Mitochondrial Enhancement Treatment in Bipolar Disorder

NCT00719706

COMPLETED NA

CoQ10 in Geriatric Bipolar Depression

NCT00720369

COMPLETED NA

Low Field Magnetic Stimulation in Mood Disorders Using the LFMS Device

NCT00578383

COMPLETED Phase 1

Transdermal Electroacupuncture for Opioid Detoxification

NCT00742170

COMPLETED NA

Riluzole in the Treatment of Bipolar Depression

NCT00544544

COMPLETED Phase 2

Effects of Pentazocine Versus Lorazepam on Manic Symptoms

NCT00431184

COMPLETED

Study of Brain Circuitry in Anxiety Disorders

NCT01849432

COMPLETED Phase 1

Augmenting Zyprexa With Naltrexone to Ameliorate Metabolic Side-Effects

NCT00567034

COMPLETED Phase 4

An Open-Label Trial of Duloxetine for the Treatment of Irritable Bowel Syndrome

NCT00401258

COMPLETED Phase 1

Effect of Uridine on GABA and High Energy Phosphate Levels in Healthy Volunteers

NCT01261260

COMPLETED Phase 3

Prescription Opioid Addiction Treatment Study (POATS)

NCT00316277

COMPLETED Phase 4

An Open-Label Trial of Memantine in the Treatment of Binge Eating Disorder

NCT00330655

COMPLETED NA

Lamotrigine Therapy in Geriatric Bipolar Depression

NCT00720473

COMPLETED Phase 4

AndroGel in Men With Major Depression and Incomplete Response to Antidepressant Treatment

NCT00304746

COMPLETED NA

Nicotine Related Brain Activity: The Influence of Smoking History and Blood Nicotine Levels

NCT01588561

COMPLETED Phase 3

The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression

NCT00125957

COMPLETED

Follow-Up Extension to the Family Study of Binge Eating Disorder

NCT00777634

COMPLETED

Understanding Brain Reward Responses in Individuals With Major Depressive Disorder

NCT00183755

COMPLETED Phase 2

Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study

NCT00217165

COMPLETED Phase 4

Study of Lamotrigine Treatment of Affective Instability in Borderline Personality Disorder

NCT00634062

COMPLETED NA

Magnetic Resonance Imaging Study of Geriatric Depression

NCT00245557

TERMINATED Phase 3

Low Field Magnetic Stimulation Treatment for Bipolar Depression

NCT00217217

COMPLETED Phase 2

Cytidine and Omega-3 Fatty Acids in Bipolar Disorder

NCT00854737

COMPLETED Phase 1

The Women's Recovery Group Study: Stage I Trial

NCT00230100

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Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 21
Phase 3 3
Phase 4 10

What is open in the Mclean Hospital pipeline

26 recruiting of 140 indexed (19% open); 92 completed (66%).

Phase mix: 13 late (III/IV) vs 40 early (I/II) (early-phase heavy).

Top condition: Major Depressive Disorder (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Mclean Hospital: open-pipeline peers nationwide

Peers matched on 140 registered trials and 19% open enrollment, not the therapeutic-area sidebar.

Mclean Hospital sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15%20% Total trials Recruiting share Mclean HospitalCase Western Reserve UniversityEastern Cooperative Oncology GroupPurdue UniversityBarbara Ann Karmanos Cancer InstituteChildren's Hospital Medical Center, CincinnatiArkansas Children's Hospital Research InstituteUniversity of Missouri-ColumbiaMontefiore Medical Center
Mclean Hospital sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Mclean Hospital sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 140 trials (± recruiting share)

Sponsors near 19% open enrollment (± trial volume)

What to do with this Mclean Hospital page

140 registered trials is a research-attention snapshot, not an endorsement of Mclean Hospital or any single study.

  • 26 of Mclean Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Major Depressive Disorder is the condition Mclean Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Major Depressive Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Mclean Hospital pipeline card: 140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.