Mayo Clinic
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).
Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.
Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.
Top-decile sponsor footprint
Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,844 total, page 9 of 57
Determining the Utility of a Behavioral Intervention in Chronic Migraine
NCT05415020
Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
NCT05530759
Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma
NCT05526417
Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
NCT05447923
Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia
NCT05111288
Pain Control for Undergoing Costal Cartilage Harvesting
NCT05285566
Evaluation of 18F-TFB PET/CT Scan in Patients With Differentiated Thyroid Cancer
NCT05575440
Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma
NCT05294367
Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy
NCT05411523
Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures
NCT05076110
Patient Derived Preclinical Models
NCT05324553
MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer
NCT05438563
Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation
NCT04502758
Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC
NCT04605913
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
NCT05269381
Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
NCT05410977
SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
NCT05222620
Hot Flashes and Neurovascular Function in Women
NCT05193968
Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity
NCT04232566
Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study
NCT05075980
Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone
NCT05033288
Examination of the Impact of CalmiGo's Stress Management Device on Vascular Heath and Cardiovascular Disease Risk.
NCT04521699
Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
NCT05045066
Gut Microbiome Studies in Patients With POEMS Syndrome and Other Plasma Cell Disorders
NCT06252948
Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture
NCT05116930
3D Ultrasound Breast Imaging
NCT04692818
Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases
NCT05122962
Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough
NCT05120934
Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough
NCT05110144
Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study
NCT05077735
Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery
NCT04730609
A Study to Evaluate Non-significant Risk Operation Magnetic Resonance Imaging for MRI Guided Ablation
NCT04880226
Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities
NCT06058650
Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
NCT05051722
Shear-wave Elastography Compared to Respiratory Function Testing
NCT04959526
Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms
NCT03446287
A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
NCT06151223
Circadian Rhythms in Human Adipose
NCT06891534
Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma
NCT03961945
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
NCT04984473
Concomitant Renal and Urinary Bladder Allograft Transplantation
NCT04626167
Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant
NCT04783155
Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction Chemotherapy
NCT06279572
Evaluating the Association Between Changes in the Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Breast Cancer
NCT05417867
Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
NCT04753996
Retina is a Marker for Cerebrovascular Heath
NCT04753970
Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury
NCT04733599
Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction
NCT04411823
Mediterranean Diet Post-liver Transplantation
NCT04672863
Ommaya Reservoir Placement for Brain Tumor Biomarker Access
NCT04692337
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 435 |
| Phase 2 | 386 |
| Phase 3 | 86 |
| Phase 4 | 166 |
Therapeutic Areas
What is open in the Mayo Clinic pipeline
544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).
Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).
Top condition: Healthy (36 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.