Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05526417 · ClinicalTrials.gov registry record · NA

Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma

A NA study of Soft Tissue Sarcoma and Stage I Soft Tissue Sarcoma of the Trunk and Extremities, sponsored by Mayo Clinic.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT05526417: Recruiting NA study of Soft Tissue Sarcoma and Stage I Soft Tissue Sarcoma of the Trunk and Extremities, sponsored by Mayo Clinic.

NCT05526417 is a NA study of Soft Tissue Sarcoma and Stage I Soft Tissue Sarcoma of the Trunk and Extremities that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 30 participants, below the 78-participant average among 55 other Soft Tissue Sarcoma trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05526417, a NA study of Soft Tissue Sarcoma and Stage I Soft Tissue Sarcoma of the Trunk and Extremities, is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This clinical trial evaluates whether patients with deep soft tissue sarcomas who receive a tailored prehabilitation exercise regimen during standard radiotherapy and prior to standard of care surgery have better recovery and surgical outcomes than those who do not. Patients undergoing surgery to soft tissue sarcomas are at high risk for post-operative disability, which is associated with high rates of depression and poor health-related quality of life. Prehabilitation is the practice of exercising before surgery to ensure that the patient is in the best possible condition. It allows patients to prepare their bodies for recovery after surgery, which may result in better surgical outcomes, recovery, and quality of life after surgery.

Primary Outcome

Univariate descriptive statistics and frequency distributions will be calculated, as appropriate for all variables. Baseline values for demographic, clinical, and outcome variables will be tabulated for the treatment groups.

Conditions Studied

Soft Tissue Sarcoma Stage I Soft Tissue Sarcoma of the Trunk and Extremities Stage II Soft Tissue Sarcoma of the Trunk and Extremities Stage III Soft Tissue Sarcoma of the Trunk and Extremities

Interventions

  • PROCEDURE Computed Tomography
  • PROCEDURE Magnetic Resonance Imaging
  • OTHER Questionnaire Administration
  • OTHER Educational Intervention
  • PROCEDURE Physical Therapy

Study Locations (1)

Arizona

  • Mayo Clinic in Arizona - Scottsdale

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2022-06-08
Est. Completion 2026-06-08
Phase NA
Mayo Clinic

2,844 total trials

What NCT05526417 shows while recruiting

NCT05526417 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 78-participant average among 55 other Soft Tissue Sarcoma trials with a reported enrollment target (62% lower).

The record links to 4 conditions, with Soft Tissue Sarcoma appearing as the primary indexed condition, and to 5 interventions - of which Computed Tomography is the first listed.

NCT05526417 reports a single indexed study location in Arizona.

Frequently Asked Questions

What is clinical trial NCT05526417 about?

NCT05526417 is a clinical study titled "Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma". This clinical trial evaluates whether patients with deep soft tissue sarcomas who receive a tailored prehabilitation exercise regimen during standard radiotherapy and prior to standard of care surgery have better recovery and surgical outcomes than those who do not. Patients undergoing surgery to so...

What is the current status of trial NCT05526417?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2022-06-08. Estimated completion is 2026-06-08.

What conditions does trial NCT05526417 study?

This clinical trial studies the following conditions: Soft Tissue Sarcoma, Stage I Soft Tissue Sarcoma of the Trunk and Extremities, Stage II Soft Tissue Sarcoma of the Trunk and Extremities, Stage III Soft Tissue Sarcoma of the Trunk and Extremities.

What interventions are being tested in trial NCT05526417?

The interventions under investigation include: Computed Tomography (PROCEDURE), Magnetic Resonance Imaging (PROCEDURE), Questionnaire Administration (OTHER), Educational Intervention (OTHER), Physical Therapy (PROCEDURE).

Who is sponsoring clinical trial NCT05526417?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05526417 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Soft Tissue Sarcoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05526417's enrollment target sits among peer trials

30 34th of 55 higher than 17 of 55 other Soft Tissue Sarcoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Soft Tissue Sarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00977977 · 30 participants · Phase 2

    Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

  • NCT01459107 · 30 participants · Phase 2

    Human Upper Extremity Allotransplantation

  • NCT01666080 · 30 participants · NA

    Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

  • NCT01720836 · 30 participants · Phase 1

    Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

More recruiting context for NCT05526417

Source: ClinicalTrials.gov NCT05526417, the US trial registry maintained by the National Library of Medicine. NCT05526417 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.