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NCT05285566 · ClinicalTrials.gov registry record · Phase 4

Pain Control for Undergoing Costal Cartilage Harvesting

A Phase 4 study of Nasal Surgery, sponsored by Mayo Clinic.

Recruiting
Registry status
Phase 4
Development phase
60
Enrollment target
1
Study location

NCT05285566: Recruiting Phase 4 study of Nasal Surgery, sponsored by Mayo Clinic.

NCT05285566 is a Phase 4 study of Nasal Surgery that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 60 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05285566, a Phase 4 study of Nasal Surgery, is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
Phase 4
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.

Primary Outcome

Measured using a visual analog scale 0=no pain and 10=worst possible

Conditions Studied

Interventions

  • DRUG Exparel
  • DRUG Xylocaine

Study Locations (1)

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2022-05-04
Est. Completion 2026-09
Phase Phase 4
Mayo Clinic

2,844 total trials

What NCT05285566 shows while recruiting

NCT05285566 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).

The record links to 1 condition, with Nasal Surgery appearing as the primary indexed condition, and to 2 interventions - of which Exparel is the first listed.

NCT05285566 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT05285566 about?

NCT05285566 is a clinical study titled "Pain Control for Undergoing Costal Cartilage Harvesting". The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.

What is the current status of trial NCT05285566?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2022-05-04. Estimated completion is 2026-09.

What conditions does trial NCT05285566 study?

This clinical trial studies the following conditions: Nasal Surgery.

What interventions are being tested in trial NCT05285566?

The interventions under investigation include: Exparel (DRUG), Xylocaine (DRUG).

Who is sponsoring clinical trial NCT05285566?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05285566 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT05285566's enrollment target sits among peer trials

60 1125th of 2000 higher than 800 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05285566, the US trial registry maintained by the National Library of Medicine. NCT05285566 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.