Mayo Clinic
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).
Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.
Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.
Top-decile sponsor footprint
Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,844 total, page 10 of 57
Cerebrospinal Fluid Biomarkers for Brain Tumors
NCT04692324
Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer
NCT04703244
CVD/PH and Voice Characteristics
NCT07311044
Prospective Sinonasal Cancer Multi-institution Study
NCT04755855
Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer
NCT04567771
MRI-Guided Cryoablation for Focal Native Prostate Cancer
NCT04797039
Deciphering Preserved Autonomic Function After Spinal Cord Injury
NCT04493372
Watchman for Patients With Atrial Fibrillation Undergoing Transcatheter Mitral Valve Repair (WATCH-TMVR)
NCT04494347
Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Lung Transplant Recipients
NCT04582279
Optimizing Brain Stimulation Parameters
NCT06617845
The Olmsted NAFLD Epidemiology Study (TONES)
NCT04365855
A Vaccine (MV-s-NAP) for the Treatment of Patients With Invasive Metastatic Breast Cancer
NCT04521764
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer
NCT04517838
NOX4 and Related Biomarkers in ADPKD
NCT04630613
Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy
NCT04082520
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
NCT04363684
Cancer Genetic Testing in Ethnic Populations
NCT04475640
Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies
NCT04047264
Oropharynx (OPX) Biomarker Trial
NCT06356272
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
NCT04099823
Obstructive Sleep Apnea Among Somali-Americans
NCT04124848
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
NCT04344769
Implications of the Human Microbiota for Health and Disease
NCT04203303
Feasibility of a Constant Pressure Skin Disk (CPSD) in Enteral Tubes.
NCT03959878
Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer
NCT03942328
Role of Gut Microbiome in Cancer Therapy
NCT05112614
Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring
NCT04799535
Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis
NCT03868592
Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)
NCT04543253
Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease
NCT03821857
A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ
NCT04144023
Insomnia in Patients With Metastatic Lung Cancer
NCT06472804
Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study
NCT06304168
Biomarkers to Predict Cancer Therapy-related Cardiotoxicity
NCT06353191
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia
NCT03865290
Wound Closure Techniques in Primary Spine Surgery
NCT04396613
Intravital Microscopy in Human Solid Tumors
NCT03823144
Understanding Mechanisms of Normal and Disordered Defecation
NCT03842007
Globus Pallidus Stimulation to Treat Insomnia
NCT04116996
Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids
NCT03818178
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
NCT03750227
Insulin Regulation of Lipolysis and Lipolysis Proteins
NCT03866408
Quality of Life After Treatment for Bladder Cancer: The Bladder Cancer Survivorship Study
NCT06350734
Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia
NCT03723564
Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT03516617
Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD)
NCT03478826
Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech
NCT01818661
Molecular Detection of Advanced Neoplasia in Pancreatic Cysts
NCT03855800
Shared Decision Making to Improve Goals of Care in the ED
NCT03833622
Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia
NCT03418038
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 435 |
| Phase 2 | 386 |
| Phase 3 | 86 |
| Phase 4 | 166 |
Therapeutic Areas
What is open in the Mayo Clinic pipeline
544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).
Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).
Top condition: Healthy (36 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.