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NCT04502758 · ClinicalTrials.gov registry record · NA
Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation
A NA study of Major Depressive Disorder and Suicidal Ideation, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT04502758: Recruiting NA study of Major Depressive Disorder and Suicidal Ideation, sponsored by Mayo Clinic.
NCT04502758 is a NA study of Major Depressive Disorder and Suicidal Ideation that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 80 participants, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04502758, a NA study of Major Depressive Disorder and Suicidal Ideation, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to gather information regarding the use of a new type of transcranial magnetic stimulation (TMS) called theta burst stimulation (TBS) for suicidal ideation in adolescents with Major Depressive Disorder (MDD). The investigators hope to learn if this TMS treatment improves suicidal ideation over 10 days and clinical outcomes over 1 year of follow-up.
Primary Outcome
Suicidal Ideation as measured by the Columbia-Suicide Severity Rating Scale (C-SSRS). This is a validated, clinician-rated tool collected to assess lifetime and ongoing suicidal ideation and behavior. The severity of ideation subscale is a 5-point ordinal scale 1-5 . 1 = Wish to be dead - 5 = Active Suicidal Ideation with Specific Plan and Intent. Assessed at baseline, 10 days and 12 months.
Conditions Studied
Interventions
- DEVICE MagVenture TMS Therapy System w/Theta Burst Stimulation
- DEVICE Sham MagVenture TMS Therapy System w/Theta Burst Stimulation
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2022-04-04 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT04502758 shows while recruiting
NCT04502758 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (79% lower).
The record links to 2 conditions, with Major Depressive Disorder appearing as the primary indexed condition, and to 2 interventions - of which MagVenture TMS Therapy System w/Theta Burst Stimulation is the first listed.
NCT04502758 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT04502758 about?
NCT04502758 is a clinical study titled "Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation". The purpose of this study is to gather information regarding the use of a new type of transcranial magnetic stimulation (TMS) called theta burst stimulation (TBS) for suicidal ideation in adolescents with Major Depressive Disorder (MDD). The investigators hope to learn if this TMS treatment improves...
What is the current status of trial NCT04502758?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2022-04-04. Estimated completion is 2027-12.
What conditions does trial NCT04502758 study?
This clinical trial studies the following conditions: Major Depressive Disorder, Suicidal Ideation.
What interventions are being tested in trial NCT04502758?
The interventions under investigation include: MagVenture TMS Therapy System w/Theta Burst Stimulation (DEVICE), Sham MagVenture TMS Therapy System w/Theta Burst Stimulation (DEVICE).
Who is sponsoring clinical trial NCT04502758?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04502758 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Major Depressive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04502758's enrollment target sits among peer trials
80 143rd of 282 higher than 134 of 282 other Major Depressive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Major Depressive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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