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NCT06279572 · ClinicalTrials.gov registry record

Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction Chemotherapy

A clinical trial of Acute Myeloid Leukemia, sponsored by Mayo Clinic.

Recruiting
Registry status
80
Enrollment target
3
Study locations

NCT06279572: Recruiting study of Acute Myeloid Leukemia, sponsored by Mayo Clinic.

NCT06279572 is a study of Acute Myeloid Leukemia that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 80 participants, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (31% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06279572, a study of Acute Myeloid Leukemia, is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
80 participants
Enrollment target
3
Study locations

Study Summary

This study investigates the immune profile of patients receiving treatment with venetoclax plus azacitidine for acute myeloid leukemia (AML). Studying the information gathered from the immune profile from blood and bone marrow samples may help researchers understand the associated responses to the treatment of patients undergoing therapy of venetoclax plus azacitidine and create future immune based treatment approaches.

Primary Outcome

Assessed using additional biospecimen samples collected during standard of care procedures (10-15 ml of peripheral blood and 10 ml of bone marrow aspirate samples). Specimens will be cryopreserved and stored for cytometry.

Conditions Studied

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Electronic Health Record Review
  • PROCEDURE Bone Marrow Aspirate

Study Locations (3)

Arizona

  • Mayo Clinic in Arizona - Scottsdale

Florida

  • Mayo Clinic in Florida - Jacksonville

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2021-04-22
Est. Completion 2026-12-31
Mayo Clinic

2,844 total trials

What NCT06279572 shows while recruiting

NCT06279572 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (31% lower).

The record links to 1 condition, with Acute Myeloid Leukemia appearing as the primary indexed condition, and to 3 interventions - of which Biospecimen Collection is the first listed.

NCT06279572 reports a single indexed study location in Arizona, Florida, Minnesota.

Frequently Asked Questions

What is clinical trial NCT06279572 about?

NCT06279572 is a clinical study titled "Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction Chemotherapy". This study investigates the immune profile of patients receiving treatment with venetoclax plus azacitidine for acute myeloid leukemia (AML). Studying the information gathered from the immune profile from blood and bone marrow samples may help researchers understand the associated responses to the t...

What is the current status of trial NCT06279572?

This trial is currently recruiting. The enrollment target is 80 participants. The study started on 2021-04-22. Estimated completion is 2026-12-31.

What conditions does trial NCT06279572 study?

This clinical trial studies the following conditions: Acute Myeloid Leukemia.

What interventions are being tested in trial NCT06279572?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Electronic Health Record Review (OTHER), Bone Marrow Aspirate (PROCEDURE).

Who is sponsoring clinical trial NCT06279572?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06279572 being conducted?

This trial has 3 study locations across Arizona, Florida, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Acute Myeloid Leukemia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06279572's enrollment target sits among peer trials

80 97th of 306 higher than 206 of 306 other Acute Myeloid Leukemia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Acute Myeloid Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06279572, the US trial registry maintained by the National Library of Medicine. NCT06279572 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.