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NCT04753970 · ClinicalTrials.gov registry record · Phase 1
Retina is a Marker for Cerebrovascular Heath
A Phase 1 study of Cerebral Small Vessel Diseases and Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT04753970 is a Phase 1 study of Cerebral Small Vessel Diseases and Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 100 participants. The trial reports 1 study location across 1 state.
The verdict
NCT04753970, a Phase 1 study of Cerebral Small Vessel Diseases and Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Cerebral small vessel disease (SVD), present in 80-94% of adults over age 65 years, increases the risk of stroke by 2-fold, and dementia by 2.3-fold. There is currently no treatment to slow SVD progression. This study aims to test whether impaired cerebral and retinal vasoreactivity may serve as biomarker for SVD progression, and to evaluate the safety and efficacy of cilostazol (antiplatelet agent with vasodilatory and anti-inflammatory properties) for the treatment of SVD.
Conditions Studied
Interventions
- DRUG Cilostazol
Study Locations (1)
Florida
- Mayo Clinic Florida - Jacksonville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-02-09 |
| Est. Completion | 2026-06 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04753970
The ClinicalTrials.gov registry entry for NCT04753970 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Cerebral Small Vessel Diseases appearing as the primary indexed condition, and to 1 intervention - of which Cilostazol is the first listed.
NCT04753970 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT04753970 about?
NCT04753970 is a clinical study titled "Retina is a Marker for Cerebrovascular Heath". Cerebral small vessel disease (SVD), present in 80-94% of adults over age 65 years, increases the risk of stroke by 2-fold, and dementia by 2.3-fold. There is currently no treatment to slow SVD progression. This study aims to test whether impaired cerebral and retinal vasoreactivity may serve as bio...
What is the current status of trial NCT04753970?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2021-02-09. Estimated completion is 2026-06.
What conditions does trial NCT04753970 study?
This clinical trial studies the following conditions: Cerebral Small Vessel Diseases, Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy, Cerebral Microbleeding, Sporadic White Matter Disease.
What interventions are being tested in trial NCT04753970?
The interventions under investigation include: Cilostazol (DRUG).
Who is sponsoring clinical trial NCT04753970?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04753970 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Cerebral Small Vessel Diseases
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