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NCT05438563 · ClinicalTrials.gov registry record · NA
MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer
A NA study of Prostate Carcinoma and Stage II Prostate Cancer AJCC v8, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05438563: Recruiting NA study of Prostate Carcinoma and Stage II Prostate Cancer AJCC v8, sponsored by Mayo Clinic.
NCT05438563 is a NA study of Prostate Carcinoma and Stage II Prostate Cancer AJCC v8 that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 100 participants, below the 1,500-participant average among 59 other Prostate Carcinoma trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05438563, a NA study of Prostate Carcinoma and Stage II Prostate Cancer AJCC v8, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This clinical trial tests whether the magnetic resonance imaging (MRI)-guided transurethral ultrasound ablation (TULSA) procedure is safe and effective in treating patients with low to intermediate grade prostate cancer. MRI-guided TULSA ablation is a minimally invasive procedure that uses an ultrasound device guided by MRI imaging to deliver high-energy sound waves, producing very high temperature to ablate (destroy) tumor cells in a targeted manner. The MRI-guided TULSA procedure may help patients avoid surgery and help improve prostate cancer patients' quality of life.
Primary Outcome
Failure is defined as: delivery of any additional intervention for prostate cancer (local or systemic, including adjuvant therapy); or metastatic disease; or prostate cancer-specific death.
Conditions Studied
Interventions
- PROCEDURE Biopsy
- OTHER Questionnaire Administration
- PROCEDURE Cystoscopy
- PROCEDURE MRI-Guided Transurethral Ultrasound Ablation
- PROCEDURE Digital Rectal Examination
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-04-06 |
| Est. Completion | 2027-03-07 |
| Phase | NA |
What NCT05438563 shows while recruiting
NCT05438563 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,500-participant average among 59 other Prostate Carcinoma trials with a reported enrollment target (93% lower).
The record links to 3 conditions, with Prostate Carcinoma appearing as the primary indexed condition, and to 5 interventions - of which Biopsy is the first listed.
NCT05438563 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT05438563 about?
NCT05438563 is a clinical study titled "MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Low to Intermediate Grade Prostate Cancer". This clinical trial tests whether the magnetic resonance imaging (MRI)-guided transurethral ultrasound ablation (TULSA) procedure is safe and effective in treating patients with low to intermediate grade prostate cancer. MRI-guided TULSA ablation is a minimally invasive procedure that uses an ultras...
What is the current status of trial NCT05438563?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2022-04-06. Estimated completion is 2027-03-07.
What conditions does trial NCT05438563 study?
This clinical trial studies the following conditions: Prostate Carcinoma, Stage II Prostate Cancer AJCC v8, Stage I Prostate Cancer AJCC v8.
What interventions are being tested in trial NCT05438563?
The interventions under investigation include: Biopsy (PROCEDURE), Questionnaire Administration (OTHER), Cystoscopy (PROCEDURE), MRI-Guided Transurethral Ultrasound Ablation (PROCEDURE), Digital Rectal Examination (PROCEDURE).
Who is sponsoring clinical trial NCT05438563?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05438563 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Prostate Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05438563's enrollment target sits among peer trials
100 26th of 59 higher than 33 of 59 other Prostate Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prostate Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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