Laureate Institute for Brain Research

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Laureate Institute for Brain Research sits in the top decile of US sponsors by registered trial count (#397 of 15,742 sponsors by registered trial count).

45 total trials 14 currently recruiting 27 completed early-phase tilt top decile by trial count

Laureate Institute for Brain Research: 45 sponsored US clinical trials, 14 recruiting.

Laureate Institute for Brain Research sponsors 45 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 27 completed. 2 of these trials are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 5 trials.

Top-decile sponsor footprint

Laureate Institute for Brain Research ranks in the top decile of sponsors by registered trial count (#397 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 57/100

27 of 31 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (87.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

45 total, page 1 of 1

RECRUITING NA

LIFU Mechanisms for PTSD in Healthcare Workers

NCT07164105

RECRUITING NA

Decoding Emotional Dynamics in Bipolar Disorder

NCT07221864

RECRUITING NA

Ultrasound Neuromodulation of Circuits and Negative Valence Systems in Treatment-Resistant Depression

NCT07166289

RECRUITING NA

Dose-Dependent Effects of Low-Intensity Focused Ultrasound

NCT07099950

RECRUITING NA

Mood and Decision-making in Methamphetamine Use Disorder

NCT06410196

RECRUITING NA

Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa

NCT06332963

RECRUITING Phase 1

Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression

NCT06088732

RECRUITING Phase 2

Evaluation of a Keto-Like Supplement on Brain Responses to Emotional Stimuli in Depression

NCT06263660

RECRUITING Phase 4

Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression

NCT06004115

RECRUITING NA

Amplification of Positivity for Alcohol Use

NCT06030154

RECRUITING NA

Gastrointestinal Interoception in Anorexia Nervosa

NCT05111977

RECRUITING Phase 1

Antiviral Treatment OF Cytomegalovirus IN Depression

NCT04724447

RECRUITING Phase 1

Neural Response to Inflammatory Challenge in Major Depressive Disorder

NCT04751331

RECRUITING NA

Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)

NCT04426461

TERMINATED NA

Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression

NCT06219681

COMPLETED

Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking

NCT06254144

COMPLETED NA

Contingency Management for Problematic Behavior Reduction in the Community

NCT06486584

COMPLETED NA

Low Intensity Ultrasound Neuromodulation of Repetitive Negative Thinking In Depression

NCT05697172

COMPLETED NA

Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression

NCT04948944

COMPLETED NA

Cognitive Process-based Real-time fMRI Neurofeedback in MDD and Rumination

NCT04941066

COMPLETED NA

Self-regulation of Prefrontal Cortex During Emotional Cognitive Control

NCT04543500

COMPLETED NA

Affective Modulation of Positivity for Alcohol Use Disorder

NCT04278365

COMPLETED NA

Augmented Mindfulness Training for Resilience in Early Life

NCT04053582

COMPLETED NA

Frontoparietal Synchronization to Modulate Drug Craving in Opioid Use Disorder

NCT03907644

COMPLETED NA

Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder

NCT03922646

COMPLETED NA

Mindfulness for Resilience in Early Life

NCT03633903

COMPLETED NA

Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide

NCT03925987

TERMINATED Phase 2

Adherence to Antidepressant Treatment in Subjects With Depression

NCT03388164

COMPLETED Phase 1

Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder

NCT03382379

COMPLETED Phase 1

Lipopolysaccharide (LPS) Challenge in Depression

NCT03142919

COMPLETED NA

Cerebellar Neuromodulation to Enhance Fear Extinction and Predict Response to Exposure Therapy

NCT03275337

COMPLETED NA

Examining the Effects of Reduced Environmental Stimulation on Anxiety

NCT03051074

COMPLETED NA

TU Tough: Mental Toughness Training for College Success

NCT02982070

TERMINATED NA

Breathing Intervention for Cardiac Anxiety

NCT02916550

COMPLETED NA

Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response

NCT02807480

COMPLETED NA

Effects of Reduced Environmental Stimulation on Eating Disorders

NCT02801084

COMPLETED NA

Neurocognitive Predictors of Behavioral Therapy Response in Depression

NCT02602340

COMPLETED NA

Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa

NCT02615119

COMPLETED Phase 2

Study of Ibuprofen Effects on Brain Function

NCT02507219

TERMINATED NA

Influenza Challenge in Mood Disorders

NCT02415166

COMPLETED NA

Examining the Effects of Reduced Environmental Stimulation on the Brain

NCT02452203

COMPLETED

Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders

NCT02450240

COMPLETED NA

Neurophysiological and Immunological Effects of the Transition From Combustible to Electronic Cigarettes

NCT02433015

COMPLETED NA

Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases

NCT02079610

COMPLETED Phase 3

Minocycline and Aspirin in the Treatment of Bipolar Depression

NCT01429272

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 3
Phase 3 1
Phase 4 1

What is open in the Laureate Institute for Brain Research pipeline

14 recruiting of 45 indexed (31% open); 27 completed (60%).

Phase mix: 2 late (III/IV) vs 8 early (I/II) (early-phase heavy).

Top condition: Depression (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Laureate Institute for Brain Research: open-pipeline peers nationwide

Peers matched on 45 registered trials and 31% open enrollment, not the therapeutic-area sidebar.

Laureate Institute for Brain Research sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 1020304050 0%10%20%30%40% Total trials Recruiting share Laureate Institute for Brain ResearchAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsAIDS Malignancy ConsortiumCambridge Health AllianceCarilion ClinicPhilips Clinical & Medical Affairs GlobalEko DevicesVarian, a Siemens Healthineers CompanyWright State University
Laureate Institute for Brain Research sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Laureate Institute for Brain Research sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 45 trials (± recruiting share)

Sponsors near 31% open enrollment (± trial volume)

What to do with this Laureate Institute for Brain Research page

45 registered trials is a research-attention snapshot, not an endorsement of Laureate Institute for Brain Research or any single study.

  • 14 of Laureate Institute for Brain Research's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Depression is the condition Laureate Institute for Brain Research studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Depression trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Laureate Institute for Brain Research pipeline card: 45 registered trials from official public datasets.Report a data error.