Laureate Institute for Brain Research
Laureate Institute for Brain Research sponsors 45 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 27 completed. 2 of these trials are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 5 trials.
Trial Pipeline
45 total, page 1 of 1
LIFU Mechanisms for PTSD in Healthcare Workers
NCT07164105
Decoding Emotional Dynamics in Bipolar Disorder
NCT07221864
Ultrasound Neuromodulation of Circuits and Negative Valence Systems in Treatment-Resistant Depression
NCT07166289
Dose-Dependent Effects of Low-Intensity Focused Ultrasound
NCT07099950
Mood and Decision-making in Methamphetamine Use Disorder
NCT06410196
Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa
NCT06332963
Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
NCT06088732
Evaluation of a Keto-Like Supplement on Brain Responses to Emotional Stimuli in Depression
NCT06263660
Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
NCT06004115
Amplification of Positivity for Alcohol Use
NCT06030154
Gastrointestinal Interoception in Anorexia Nervosa
NCT05111977
Antiviral Treatment OF Cytomegalovirus IN Depression
NCT04724447
Neural Response to Inflammatory Challenge in Major Depressive Disorder
NCT04751331
Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
NCT04426461
Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression
NCT06219681
Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking
NCT06254144
Contingency Management for Problematic Behavior Reduction in the Community
NCT06486584
Low Intensity Ultrasound Neuromodulation of Repetitive Negative Thinking In Depression
NCT05697172
Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression
NCT04948944
Cognitive Process-based Real-time fMRI Neurofeedback in MDD and Rumination
NCT04941066
Self-regulation of Prefrontal Cortex During Emotional Cognitive Control
NCT04543500
Affective Modulation of Positivity for Alcohol Use Disorder
NCT04278365
Augmented Mindfulness Training for Resilience in Early Life
NCT04053582
Frontoparietal Synchronization to Modulate Drug Craving in Opioid Use Disorder
NCT03907644
Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder
NCT03922646
Mindfulness for Resilience in Early Life
NCT03633903
Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide
NCT03925987
Adherence to Antidepressant Treatment in Subjects With Depression
NCT03388164
Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder
NCT03382379
Lipopolysaccharide (LPS) Challenge in Depression
NCT03142919
Cerebellar Neuromodulation to Enhance Fear Extinction and Predict Response to Exposure Therapy
NCT03275337
Examining the Effects of Reduced Environmental Stimulation on Anxiety
NCT03051074
TU Tough: Mental Toughness Training for College Success
NCT02982070
Breathing Intervention for Cardiac Anxiety
NCT02916550
Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response
NCT02807480
Effects of Reduced Environmental Stimulation on Eating Disorders
NCT02801084
Neurocognitive Predictors of Behavioral Therapy Response in Depression
NCT02602340
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
NCT02615119
Study of Ibuprofen Effects on Brain Function
NCT02507219
Influenza Challenge in Mood Disorders
NCT02415166
Examining the Effects of Reduced Environmental Stimulation on the Brain
NCT02452203
Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders
NCT02450240
Neurophysiological and Immunological Effects of the Transition From Combustible to Electronic Cigarettes
NCT02433015
Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases
NCT02079610
Minocycline and Aspirin in the Treatment of Bipolar Depression
NCT01429272
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 3 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Therapeutic Areas
What the Pipeline for Laureate Institute for Brain Research Shows
According to the ClinicalTrials.gov registry, Laureate Institute for Brain Research is linked to 45 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 31% of the sponsor's indexed portfolio, and 27 are already marked complete, representing roughly 60% of the total.
The phase mix for Laureate Institute for Brain Research reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 8 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Laureate Institute for Brain Research is Depression with 5 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.