Laureate Institute for Brain Research

45 total trials 14 currently recruiting 27 completed

Laureate Institute for Brain Research sponsors 45 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 27 completed. 2 of these trials are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 5 trials.

Trial Pipeline

45 total, page 1 of 1

RECRUITING NA

LIFU Mechanisms for PTSD in Healthcare Workers

NCT07164105

RECRUITING NA

Decoding Emotional Dynamics in Bipolar Disorder

NCT07221864

RECRUITING NA

Ultrasound Neuromodulation of Circuits and Negative Valence Systems in Treatment-Resistant Depression

NCT07166289

RECRUITING NA

Dose-Dependent Effects of Low-Intensity Focused Ultrasound

NCT07099950

RECRUITING NA

Mood and Decision-making in Methamphetamine Use Disorder

NCT06410196

RECRUITING NA

Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa

NCT06332963

RECRUITING Phase 1

Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression

NCT06088732

RECRUITING Phase 2

Evaluation of a Keto-Like Supplement on Brain Responses to Emotional Stimuli in Depression

NCT06263660

RECRUITING Phase 4

Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression

NCT06004115

RECRUITING NA

Amplification of Positivity for Alcohol Use

NCT06030154

RECRUITING NA

Gastrointestinal Interoception in Anorexia Nervosa

NCT05111977

RECRUITING Phase 1

Antiviral Treatment OF Cytomegalovirus IN Depression

NCT04724447

RECRUITING Phase 1

Neural Response to Inflammatory Challenge in Major Depressive Disorder

NCT04751331

RECRUITING NA

Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)

NCT04426461

TERMINATED NA

Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression

NCT06219681

COMPLETED

Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking

NCT06254144

COMPLETED NA

Contingency Management for Problematic Behavior Reduction in the Community

NCT06486584

COMPLETED NA

Low Intensity Ultrasound Neuromodulation of Repetitive Negative Thinking In Depression

NCT05697172

COMPLETED NA

Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression

NCT04948944

COMPLETED NA

Cognitive Process-based Real-time fMRI Neurofeedback in MDD and Rumination

NCT04941066

COMPLETED NA

Self-regulation of Prefrontal Cortex During Emotional Cognitive Control

NCT04543500

COMPLETED NA

Affective Modulation of Positivity for Alcohol Use Disorder

NCT04278365

COMPLETED NA

Augmented Mindfulness Training for Resilience in Early Life

NCT04053582

COMPLETED NA

Frontoparietal Synchronization to Modulate Drug Craving in Opioid Use Disorder

NCT03907644

COMPLETED NA

Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder

NCT03922646

COMPLETED NA

Mindfulness for Resilience in Early Life

NCT03633903

COMPLETED NA

Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide

NCT03925987

TERMINATED Phase 2

Adherence to Antidepressant Treatment in Subjects With Depression

NCT03388164

COMPLETED Phase 1

Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder

NCT03382379

COMPLETED Phase 1

Lipopolysaccharide (LPS) Challenge in Depression

NCT03142919

COMPLETED NA

Cerebellar Neuromodulation to Enhance Fear Extinction and Predict Response to Exposure Therapy

NCT03275337

COMPLETED NA

Examining the Effects of Reduced Environmental Stimulation on Anxiety

NCT03051074

COMPLETED NA

TU Tough: Mental Toughness Training for College Success

NCT02982070

TERMINATED NA

Breathing Intervention for Cardiac Anxiety

NCT02916550

COMPLETED NA

Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response

NCT02807480

COMPLETED NA

Effects of Reduced Environmental Stimulation on Eating Disorders

NCT02801084

COMPLETED NA

Neurocognitive Predictors of Behavioral Therapy Response in Depression

NCT02602340

COMPLETED NA

Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa

NCT02615119

COMPLETED Phase 2

Study of Ibuprofen Effects on Brain Function

NCT02507219

TERMINATED NA

Influenza Challenge in Mood Disorders

NCT02415166

COMPLETED NA

Examining the Effects of Reduced Environmental Stimulation on the Brain

NCT02452203

COMPLETED

Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders

NCT02450240

COMPLETED NA

Neurophysiological and Immunological Effects of the Transition From Combustible to Electronic Cigarettes

NCT02433015

COMPLETED NA

Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases

NCT02079610

COMPLETED Phase 3

Minocycline and Aspirin in the Treatment of Bipolar Depression

NCT01429272

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 3
Phase 3 1
Phase 4 1

What the Pipeline for Laureate Institute for Brain Research Shows

According to the ClinicalTrials.gov registry, Laureate Institute for Brain Research is linked to 45 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 31% of the sponsor's indexed portfolio, and 27 are already marked complete, representing roughly 60% of the total.

The phase mix for Laureate Institute for Brain Research reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 8 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Laureate Institute for Brain Research is Depression with 5 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.