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NCT06410196 · ClinicalTrials.gov registry record · NA

Mood and Decision-making in Methamphetamine Use Disorder

A NA study of Methamphetamine Abuse, sponsored by Laureate Institute for Brain Research.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT06410196: Recruiting NA study of Methamphetamine Abuse, sponsored by Laureate Institute for Brain Research.

NCT06410196 is a NA study of Methamphetamine Abuse that is actively recruiting participants, run by Laureate Institute for Brain Research. The registered enrollment target is 80 participants, below the 203-participant average among 15 other Methamphetamine Abuse trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06410196, a NA study of Methamphetamine Abuse, is actively recruiting participants, sponsored by Laureate Institute for Brain Research.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

In this project, the investigators examine behavior and associated brain activity during explore-exploit decision-making tasks performed pre- and post-modulation of affective state using autobiographical memory recall. The investigators hypothesize that a positive memory recall will reduce negative affective state, reduce explore-exploit biases and normalize the associated brain activity. The investigators propose a randomized double-blind, sham-controlled trial of positive autobiographical memory recall with 80 adults (n=40 per arm) with methamphetamine use disorder (MUD) currently involved in abstinence only treatment centers.

Primary Outcome

Use of PANAS-PA and PANAS-NA questionnaires to measure positive and negative affect respectively (scale range: 0=low; 60=high; low mood is defined as low positive and/or high negative affect)

Conditions Studied

Interventions

  • BEHAVIORAL Mood modulation

Study Locations (1)

Oklahoma

  • Laureate Institute for Brain Research - Tulsa

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2024-07-26
Est. Completion 2027-07-01
Phase NA

What NCT06410196 shows while recruiting

NCT06410196 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 203-participant average among 15 other Methamphetamine Abuse trials with a reported enrollment target (61% lower).

The record links to 1 condition, with Methamphetamine Abuse appearing as the primary indexed condition, and to 1 intervention - of which Mood modulation is the first listed.

NCT06410196 reports a single indexed study location in Oklahoma.

Frequently Asked Questions

What is clinical trial NCT06410196 about?

NCT06410196 is a clinical study titled "Mood and Decision-making in Methamphetamine Use Disorder". In this project, the investigators examine behavior and associated brain activity during explore-exploit decision-making tasks performed pre- and post-modulation of affective state using autobiographical memory recall. The investigators hypothesize that a positive memory recall will reduce negative ...

What is the current status of trial NCT06410196?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2024-07-26. Estimated completion is 2027-07-01.

What conditions does trial NCT06410196 study?

This clinical trial studies the following conditions: Methamphetamine Abuse.

What interventions are being tested in trial NCT06410196?

The interventions under investigation include: Mood modulation (BEHAVIORAL).

Who is sponsoring clinical trial NCT06410196?

This trial is sponsored by Laureate Institute for Brain Research, which has 45 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06410196 being conducted?

This trial has 1 study location across Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Methamphetamine Abuse

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06410196's enrollment target sits among peer trials

80 8th of 15 higher than 8 of 15 other Methamphetamine Abuse trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Methamphetamine Abuse trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06410196, the US trial registry maintained by the National Library of Medicine. NCT06410196 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.