AIDS Malignancy Consortium

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, AIDS Malignancy Consortium sits in the top decile of US sponsors by registered trial count (#397 of 15,742 sponsors by registered trial count).

45 total trials 5 currently recruiting 30 completed early-phase tilt top decile by trial count

AIDS Malignancy Consortium: 45 sponsored US clinical trials, 5 recruiting.

AIDS Malignancy Consortium sponsors 45 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 30 completed. 3 of these trials are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infection, with 7 trials.

Top-decile sponsor footprint

AIDS Malignancy Consortium ranks in the top decile of sponsors by registered trial count (#397 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 48/100

30 of 36 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

45 total, page 1 of 1

RECRUITING Phase 1

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

NCT05077527

RECRUITING Phase 2

Trial of Ixazomib for Kaposi Sarcoma

NCT04305691

RECRUITING

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

NCT05663502

RECRUITING NA

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

NCT04949464

RECRUITING Early Phase 1

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

NCT04139304

ACTIVE NOT RECRUITING Phase 1

Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant

NCT02797470

ACTIVE NOT RECRUITING Phase 2

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

NCT02437851

NOT YET RECRUITING Phase 2

Nirogacestat in Patients With Kaposi Sarcoma

NCT07539454

NOT YET RECRUITING Phase 2

Epcoritamab in Combination With Dose Adjusted EPOCH-R for High-risk Burkitt Lymphoma (BL), The BEDROCK Study

NCT07662928

COMPLETED

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

NCT05510908

COMPLETED

Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell

NCT05784415

COMPLETED

Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions

NCT04276935

COMPLETED Phase 2

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

NCT03603808

COMPLETED Phase 2

sEphB4-HSA in Treating Patients With Kaposi Sarcoma

NCT02799485

COMPLETED Phase 2

Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma

NCT03077451

TERMINATED

Clinical and Genomic Factors for Prognosis of AIDS Primary Effusion Lymphoma

NCT02823327

COMPLETED Phase 3

Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

NCT02059499

COMPLETED

Health-Related Symptom Questionnaires in Measuring Quality of Life in HIV-Infected Participants Treated or Monitored for Anal Lesions

NCT02418494

COMPLETED Phase 3

Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions

NCT02135419

COMPLETED NA

Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV

NCT01946139

TERMINATED Phase 1

Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection

NCT01249443

COMPLETED

Factors Affecting Patient Participation in AIDS Malignancy Clinical Trials Consortium Clinical Trials

NCT01946217

TERMINATED

Collecting and Studying Tissue Samples From Patients With HIV-Associated Malignancies

NCT01567722

COMPLETED Phase 2

Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males

NCT01209325

TERMINATED

Biomarkers in Blood Samples From Patients With HIV Infection and Stage III or Stage IV Hodgkin Lymphoma Undergoing Chemotherapy

NCT01319526

COMPLETED Phase 3

Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia

NCT01164722

COMPLETED

Study of Blood and Tissue Samples From Patients With Aggressive Non-Hodgkin B-Cell Lymphoma or Hodgkin Lymphoma

NCT00981097

COMPLETED

Human Papilloma Virus Infection in HIV-Positive Indian Men Who Have Sex With Men

NCT00919997

TERMINATED Phase 1

Liposomal Daunorubicin in Treating Patients With HIV-Related Kaposi's Sarcoma

NCT00427414

TERMINATED Phase 1

PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma

NCT00686842

COMPLETED

Detecting Anal and Genital Human Papillomavirus Infection and Squamous Intraepithelial Lesions in HIV-Positive Patients Enrolled in AIDS Cancer Clinical Trials

NCT00695422

COMPLETED Phase 1

Bortezomib, Ifosfamide, Carboplatin, and Etoposide, With or Without Rituximab, in Treating Patients With Relapsed or Refractory AIDS-Related Non-Hodgkin Lymphoma

NCT00598169

COMPLETED Phase 2

Human Papillomavirus Vaccine Therapy in Treating Men With HIV-1 Infection

NCT00513526

COMPLETED Phase 1

Sirolimus in Treating Patients With HIV-Related Kaposi's Sarcoma

NCT00450320

COMPLETED Phase 2

Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus

NCT00550589

COMPLETED Phase 2

Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed AIDS-Related B-Cell Non-Hodgkin's Lymphoma

NCT00389818

COMPLETED Phase 2

Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma

NCT00392834

COMPLETED Phase 2

Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer

NCT00324415

COMPLETED Phase 2

Imatinib Mesylate in Treating Patients With HIV-Related Kaposi's Sarcoma

NCT00090987

COMPLETED NA

Valproic Acid in Treating Patients With Kaposi's Sarcoma

NCT00075777

COMPLETED Phase 1

Infrared Coagulation in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia

NCT00066430

COMPLETED Phase 2

Combination Chemotherapy Followed By Antiviral Therapy and Interferon Alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma

NCT00041327

COMPLETED Phase 2

Chemotherapy Followed By Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory AIDS-Related Lymphoma

NCT00005824

COMPLETED Phase 2

Zidovudine Plus Interleukin-2 and Ganciclovir in Treating Patients With AIDS-Related Primary Central Nervous System Lymphoma

NCT00006264

COMPLETED Phase 2

SU5416 in Treating Patients With AIDS-Related Kaposi's Sarcoma

NCT00005042

What is open in the AIDS Malignancy Consortium pipeline

5 recruiting of 45 indexed (11% open); 30 completed (67%).

Phase mix: 3 late (III/IV) vs 27 early (I/II) (early-phase heavy).

Top condition: HIV Infection (7 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

AIDS Malignancy Consortium: open-pipeline peers nationwide

Peers matched on 45 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

AIDS Malignancy Consortium sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 01020304050 0%5%10%15%20%25%30% Total trials Recruiting share AIDS Malignancy ConsortiumAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsCambridge Health AllianceCarilion ClinicGenmabADC Therapeutics S.A.Adrian VellaAmylyx PharmaceuticalsAprea Therapeutics
AIDS Malignancy Consortium sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

AIDS Malignancy Consortium sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 45 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this AIDS Malignancy Consortium page

45 registered trials is a research-attention snapshot, not an endorsement of AIDS Malignancy Consortium or any single study.

  • 5 of AIDS Malignancy Consortium's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infection is the condition AIDS Malignancy Consortium studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infection trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

AIDS Malignancy Consortium pipeline card: 45 registered trials from official public datasets.Report a data error.