Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections sponsors 45 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 38 completed. 10 of these trials are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV-1-infection, with 8 trials.
Trial Pipeline
45 total, page 1 of 1
Menopausal HT for Women Living With HIV (HoT)
NCT06856174
Observational PIC Destination Cohort
NCT05985642
Consent for Use of Stored Patient Specimens for Future Testing
NCT00031408
Doravirine for Obese Persons on Integrase Inhibitors and Tenofovir Alafenamide
NCT04636437
Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection
NCT04042740
Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy
NCT03819114
Monitoring SOF/VEL in Treatment Naïve, HCV Participants With Active Infection
NCT03512210
PREPARE (A5361s) Ancillary Study of REPRIEVE (A5332)
NCT03070223
Biomarkers to Predict Time to Plasma HIV RNA Rebound
NCT03001128
Early ART to Limit Infection and Establishment of Reservoir
NCT02859558
Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers
NCT02706717
12 Weeks of Ledipasvir (LDV)/Sofosbuvir (SOF) With Weight-based Ribavirin vs. 24 Weeks of LDV/SOF
NCT02605304
Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)
NCT02440789
Dolutegravir Plus Lamivudine Dual Therapy in Treatment Naïve HIV-1 Patients
NCT02582684
Sitagliptin for Reducing Inflammation and Immune Activation
NCT02513771
Evaluating Pharmacokinetic Interactions With Vaginal Ring Contraceptives and ART
NCT01903031
Modulation of Immune Activation by Aspirin
NCT02155985
Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery
NCT01969058
Sofosbuvir-Containing Regimens Without Interferon For Treatment of Acute Hepatitis C Virus (HCV) Infection
NCT02128217
Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)
NCT01928927
FTC/RPV/TDF on T-Cell Activation, CD4+ T-Cell Count, Inflammatory Biomarkers and Viral Reservoir
NCT01777997
Bone, Immunologic, and Virologic Effects of a Antiretroviral Regimen
NCT01400412
Endothelial Function, Lipoproteins, and Inflammation With Low HDL Cholesterol in HIV: ER Niacin Versus Fenofibrate
NCT01426438
Sevelamer for Reducing Endotoxemia and Immune Activation
NCT01543958
High Dose Vitamin D and Calcium for Bone Health in Individuals Initiating HAART
NCT01403051
Rifaximin as a Modulator of Microbial Translocation and Immune Activation
NCT01466595
Pharmacokinetic Interactions Between DMPA and LPV/r Among HIV-Infected Women
NCT01296152
Atorvastatin on Biomarkers of Inflammation, Coagulopathy, Angiogenesis & T-cells
NCT01351025
Telephone Support to Improve Adherence to Anti-HIV Medications
NCT00988442
Examining the Incidence of Oral Human Papillomavirus (HPV) Shedding and Oral Warts After Beginning HAART in HIV-Infected Adults
NCT01029249
Durability of Adherence in Self-Management of HIV
NCT00991302
Assessing HIV-Related Oral Mucosal Disease and Using Saliva to Measure Viral Load
NCT00959413
Impact of Antiretroviral Therapy on Metabolic, Skeletal, and Cardiovascular Parameters
NCT00851799
Comparative Study of Three NNRTI-Sparing HAART Regimens
NCT00811954
Safety and Effectiveness of Raltegravir Plus Darunavir/Ritonavir in Treatment-Naive HIV-Infected Adults
NCT00830804
Pioglitazone Before Peginterferon and Ribavirin for Hepatitis C Infection in HIV/HCV-Coinfected Patients With Insulin Resistance
NCT00665353
Chloroquine for Reducing Immune Activation in HIV- Infected Individuals
NCT00819390
Adding Maraviroc to Antiretroviral Therapy for Suboptimal CD4 T-Cell Recovery Despite Sustained Virologic Suppression
NCT00709111
HIV Treatment Reinitiation in Women Who Received Anti-HIV Drugs to Prevent Mother-to-Child Transmission of HIV
NCT00442962
Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults
NCT00361257
Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis
NCT00108862
Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults
NCT00118898
Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings
NCT00084136
Nine Month Course of Anti-HIV Medications for People Recently Infected With HIV
NCT00090779
Long-Term Data Collection From Participants in Adult AIDS Clinical Trials
NCT00001137
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 24 |
| Phase 3 | 3 |
| Phase 4 | 7 |
Therapeutic Areas
What the Pipeline for Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections Shows
According to the ClinicalTrials.gov registry, Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections is linked to 45 US clinical trials across every stage of research activity. Of those, 2 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 38 are already marked complete, representing roughly 84% of the total.
The phase mix for Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections reports 10 late-stage studies (Phase 3 and Phase 4 combined) and 26 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections is HIV-1-infection with 8 linked trials, and 7 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.