Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

45 total trials 2 currently recruiting 38 completed

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections sponsors 45 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 38 completed. 10 of these trials are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV-1-infection, with 8 trials.

Trial Pipeline

45 total, page 1 of 1

RECRUITING Phase 4

Menopausal HT for Women Living With HIV (HoT)

NCT06856174

RECRUITING

Observational PIC Destination Cohort

NCT05985642

ACTIVE NOT RECRUITING

Consent for Use of Stored Patient Specimens for Future Testing

NCT00031408

COMPLETED Phase 4

Doravirine for Obese Persons on Integrase Inhibitors and Tenofovir Alafenamide

NCT04636437

COMPLETED Phase 2

Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection

NCT04042740

COMPLETED Phase 2

Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy

NCT03819114

COMPLETED Phase 4

Monitoring SOF/VEL in Treatment Naïve, HCV Participants With Active Infection

NCT03512210

COMPLETED Phase 3

PREPARE (A5361s) Ancillary Study of REPRIEVE (A5332)

NCT03070223

COMPLETED

Biomarkers to Predict Time to Plasma HIV RNA Rebound

NCT03001128

COMPLETED Phase 2

Early ART to Limit Infection and Establishment of Reservoir

NCT02859558

COMPLETED Phase 2

Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers

NCT02706717

TERMINATED Phase 2

12 Weeks of Ledipasvir (LDV)/Sofosbuvir (SOF) With Weight-based Ribavirin vs. 24 Weeks of LDV/SOF

NCT02605304

COMPLETED Phase 1

Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)

NCT02440789

COMPLETED Phase 2

Dolutegravir Plus Lamivudine Dual Therapy in Treatment Naïve HIV-1 Patients

NCT02582684

COMPLETED Phase 2

Sitagliptin for Reducing Inflammation and Immune Activation

NCT02513771

COMPLETED Phase 2

Evaluating Pharmacokinetic Interactions With Vaginal Ring Contraceptives and ART

NCT01903031

COMPLETED Phase 2

Modulation of Immune Activation by Aspirin

NCT02155985

COMPLETED Phase 2

Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery

NCT01969058

COMPLETED Phase 1

Sofosbuvir-Containing Regimens Without Interferon For Treatment of Acute Hepatitis C Virus (HCV) Infection

NCT02128217

COMPLETED Phase 2

Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)

NCT01928927

COMPLETED Phase 4

FTC/RPV/TDF on T-Cell Activation, CD4+ T-Cell Count, Inflammatory Biomarkers and Viral Reservoir

NCT01777997

COMPLETED Phase 2

Bone, Immunologic, and Virologic Effects of a Antiretroviral Regimen

NCT01400412

COMPLETED Phase 2

Endothelial Function, Lipoproteins, and Inflammation With Low HDL Cholesterol in HIV: ER Niacin Versus Fenofibrate

NCT01426438

COMPLETED Phase 2

Sevelamer for Reducing Endotoxemia and Immune Activation

NCT01543958

COMPLETED Phase 2

High Dose Vitamin D and Calcium for Bone Health in Individuals Initiating HAART

NCT01403051

COMPLETED Phase 2

Rifaximin as a Modulator of Microbial Translocation and Immune Activation

NCT01466595

COMPLETED Phase 2

Pharmacokinetic Interactions Between DMPA and LPV/r Among HIV-Infected Women

NCT01296152

COMPLETED Phase 2

Atorvastatin on Biomarkers of Inflammation, Coagulopathy, Angiogenesis & T-cells

NCT01351025

TERMINATED Phase 2

Telephone Support to Improve Adherence to Anti-HIV Medications

NCT00988442

COMPLETED

Examining the Incidence of Oral Human Papillomavirus (HPV) Shedding and Oral Warts After Beginning HAART in HIV-Infected Adults

NCT01029249

COMPLETED NA

Durability of Adherence in Self-Management of HIV

NCT00991302

COMPLETED

Assessing HIV-Related Oral Mucosal Disease and Using Saliva to Measure Viral Load

NCT00959413

COMPLETED

Impact of Antiretroviral Therapy on Metabolic, Skeletal, and Cardiovascular Parameters

NCT00851799

COMPLETED Phase 3

Comparative Study of Three NNRTI-Sparing HAART Regimens

NCT00811954

COMPLETED Phase 2

Safety and Effectiveness of Raltegravir Plus Darunavir/Ritonavir in Treatment-Naive HIV-Infected Adults

NCT00830804

COMPLETED Phase 2

Pioglitazone Before Peginterferon and Ribavirin for Hepatitis C Infection in HIV/HCV-Coinfected Patients With Insulin Resistance

NCT00665353

COMPLETED Phase 2

Chloroquine for Reducing Immune Activation in HIV- Infected Individuals

NCT00819390

COMPLETED NA

Adding Maraviroc to Antiretroviral Therapy for Suboptimal CD4 T-Cell Recovery Despite Sustained Virologic Suppression

NCT00709111

COMPLETED Phase 4

HIV Treatment Reinitiation in Women Who Received Anti-HIV Drugs to Prevent Mother-to-Child Transmission of HIV

NCT00442962

TERMINATED Phase 2

Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults

NCT00361257

COMPLETED Phase 4

Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis

NCT00108862

COMPLETED Phase 3

Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults

NCT00118898

COMPLETED Phase 4

Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings

NCT00084136

TERMINATED Phase 2

Nine Month Course of Anti-HIV Medications for People Recently Infected With HIV

NCT00090779

COMPLETED

Long-Term Data Collection From Participants in Adult AIDS Clinical Trials

NCT00001137

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 24
Phase 3 3
Phase 4 7

What the Pipeline for Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections Shows

According to the ClinicalTrials.gov registry, Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections is linked to 45 US clinical trials across every stage of research activity. Of those, 2 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 38 are already marked complete, representing roughly 84% of the total.

The phase mix for Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections reports 10 late-stage studies (Phase 3 and Phase 4 combined) and 26 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections is HIV-1-infection with 8 linked trials, and 7 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.