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NCT02807480 · ClinicalTrials.gov registry record · NA

Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response

A NA study of Generalized Anxiety Disorder, sponsored by Laureate Institute for Brain Research.

Completed
Registry status
NA
Development phase
121
Enrollment target
1
Study location

NCT02807480 is a NA study of Generalized Anxiety Disorder that has completed, run by Laureate Institute for Brain Research. The registered enrollment target is 121 participants, below the 212-participant average among 48 other Generalized Anxiety Disorder trials with a reported enrollment target (43% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02807480, a NA study of Generalized Anxiety Disorder, has completed, sponsored by Laureate Institute for Brain Research.

COMPLETED
Registry status
NA
Development phase
121 participants
Enrollment target
1
Study location

Study Summary

This project aims to identify brain and behavioral characteristics of individuals experiencing symptoms of generalized anxiety disorder that will predict the effectiveness of Exposure-based therapy versus Behavioral Activation Therapy. Brain imaging aspects of the study will use functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). Behavioral assessments will include self-report questionnaires, computer-based and observational tasks, and interviews. Assessments will focus on how individuals process positive information (such as reward) and negative information (such as distressing images), as well as how people make decisions. These assessments will be conducted across 2-3 in-person sessions prior to beginning the treatment, and will be repeated across 2-3 in-person sessions after completing treatment. A blood draw will also be conducted pre- and post- treatment. Both the Exposure-based and Behavior Activation therapy will consist of 10, 90-minute weekly therapy sessions conducted in small groups.

Interventions

  • DEVICE Magnetic resonance imaging (MRI)
  • BEHAVIORAL Exposure-based therapy
  • BEHAVIORAL Surveys and Interviews
  • BEHAVIORAL Behavioral Activation therapy
  • BEHAVIORAL Computer-based behavioral assessment

Study Locations (1)

Oklahoma

  • Laureate Institute for Brain Research - Tulsa

Trial Details

FieldValue
Enrollment Target 121 participants
Start Date 2016-06
Est. Completion 2022-03-04
Phase NA

What the Registry Record Tells You About NCT02807480

The ClinicalTrials.gov registry entry for NCT02807480 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 121 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 212-participant average among 48 other Generalized Anxiety Disorder trials with a reported enrollment target (43% lower). The listed sponsor is Laureate Institute for Brain Research, which has 45 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Generalized Anxiety Disorder appearing as the primary indexed condition, and to 5 interventions - of which Magnetic resonance imaging (MRI) is the first listed.

NCT02807480 reports 1 study location spanning 1 distinct geographic area - top geographies include Oklahoma.

Frequently Asked Questions

What is clinical trial NCT02807480 about?

NCT02807480 is a clinical study titled "Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response". This project aims to identify brain and behavioral characteristics of individuals experiencing symptoms of generalized anxiety disorder that will predict the effectiveness of Exposure-based therapy versus Behavioral Activation Therapy. Brain imaging aspects of the study will use functional magnetic ...

What is the current status of trial NCT02807480?

This trial is currently completed. It is a NA study. The enrollment target is 121 participants. The study started on 2016-06. Estimated completion is 2022-03-04.

What conditions does trial NCT02807480 study?

This clinical trial studies the following conditions: Generalized Anxiety Disorder.

What interventions are being tested in trial NCT02807480?

The interventions under investigation include: Magnetic resonance imaging (MRI) (DEVICE), Exposure-based therapy (BEHAVIORAL), Surveys and Interviews (BEHAVIORAL), Behavioral Activation therapy (BEHAVIORAL), Computer-based behavioral assessment (BEHAVIORAL).

Who is sponsoring clinical trial NCT02807480?

This trial is sponsored by Laureate Institute for Brain Research, which has 45 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02807480 being conducted?

This trial has 1 study location across Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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