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NCT07099950 · ClinicalTrials.gov registry record · NA

Dose-Dependent Effects of Low-Intensity Focused Ultrasound

A NA study of Healthy (Controls), sponsored by Laureate Institute for Brain Research.

Recruiting
Registry status
NA
Development phase
66
Enrollment target
1
Study location

NCT07099950 is a NA study of Healthy (Controls) that is actively recruiting participants, run by Laureate Institute for Brain Research. The registered enrollment target is 66 participants, below the 117-participant average among 16 other Healthy (Controls) trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07099950, a NA study of Healthy (Controls), is actively recruiting participants, sponsored by Laureate Institute for Brain Research.

RECRUITING
Registry status
NA
Development phase
66 participants
Enrollment target
1
Study location

Study Summary

Low-intensity focused ultrasound (LIFU) has emerged as a tool to modulate the activity of deep brain structures noninvasively and reversibly, with anatomical precision. Following the results of a pilot study in which the investigators observed target engagement when LIFU was applied to the anterior limb of the internal capsule, the investigators now propose to determine the dose-response relationships of LIFU when applied to deep white matter tracts of the human brain. The investigators hope a successful study will be rapidly translatable into clinical trials seeking to understand mechanistic brain circuit-symptom relationships in major psychiatric disorders.

Conditions Studied

Interventions

  • OTHER Low-intensity focused ultrasound

Study Locations (1)

Oklahoma

  • Laureate Institute for Brain Research - Tulsa

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2025-04-22
Est. Completion 2026-12
Phase NA

What the Registry Record Tells You About NCT07099950

The ClinicalTrials.gov registry entry for NCT07099950 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 117-participant average among 16 other Healthy (Controls) trials with a reported enrollment target (44% lower). The listed sponsor is Laureate Institute for Brain Research, which has 45 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy (Controls) appearing as the primary indexed condition, and to 1 intervention - of which Low-intensity focused ultrasound is the first listed.

NCT07099950 reports 1 study location spanning 1 distinct geographic area - top geographies include Oklahoma.

Frequently Asked Questions

What is clinical trial NCT07099950 about?

NCT07099950 is a clinical study titled "Dose-Dependent Effects of Low-Intensity Focused Ultrasound". Low-intensity focused ultrasound (LIFU) has emerged as a tool to modulate the activity of deep brain structures noninvasively and reversibly, with anatomical precision. Following the results of a pilot study in which the investigators observed target engagement when LIFU was applied to the anterior ...

What is the current status of trial NCT07099950?

This trial is currently recruiting. It is a NA study. The enrollment target is 66 participants. The study started on 2025-04-22. Estimated completion is 2026-12.

What conditions does trial NCT07099950 study?

This clinical trial studies the following conditions: Healthy (Controls).

What interventions are being tested in trial NCT07099950?

The interventions under investigation include: Low-intensity focused ultrasound (OTHER).

Who is sponsoring clinical trial NCT07099950?

This trial is sponsored by Laureate Institute for Brain Research, which has 45 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07099950 being conducted?

This trial has 1 study location across Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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