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NCT06219681 · ClinicalTrials.gov registry record · NA
Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression
A NA study, sponsored by Laureate Institute for Brain Research.
- Terminated
- Registry status
- NA
- Development phase
- 54
- Enrollment target
NCT06219681 is a NA study that was terminated before completion, run by Laureate Institute for Brain Research. The registered enrollment target is 54 participants.
The verdict
NCT06219681, a NA study, was terminated before completion, sponsored by Laureate Institute for Brain Research.
- TERMINATED
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
Study Summary
In this project, the investigators use real-time fMRI neurofeedback (rtfMRI-nf) to causally relate dysfunction of right anterior insula (rAI) and right superior temporal sulcus (rSTS) connectivity with the intensity of repetitive negative thinking (RNT). The investigators hypothesize that rtfMRI-nf reducing rAI-rSTS connectivity would reduce RNT. The investigators propose a randomized double-blind, sham-controlled trial of rtfMRI-nf with 110 young adults (n=55/arm) with major depressive disorder (MDD) and high trait-RNT levels.
Interventions
- BEHAVIORAL Active neurofeedback
- BEHAVIORAL Sham neurofeedback
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2024-01-12 |
| Est. Completion | 2025-04-04 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06219681
The ClinicalTrials.gov registry entry for NCT06219681 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Laureate Institute for Brain Research, which has 45 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Active neurofeedback is the first listed.
NCT06219681 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06219681 about?
NCT06219681 is a clinical study titled "Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression". In this project, the investigators use real-time fMRI neurofeedback (rtfMRI-nf) to causally relate dysfunction of right anterior insula (rAI) and right superior temporal sulcus (rSTS) connectivity with the intensity of repetitive negative thinking (RNT). The investigators hypothesize that rtfMRI-nf ...
What is the current status of trial NCT06219681?
This trial is currently terminated. It is a NA study. The enrollment target is 54 participants. The study started on 2024-01-12. Estimated completion is 2025-04-04.
What interventions are being tested in trial NCT06219681?
The interventions under investigation include: Active neurofeedback (BEHAVIORAL), Sham neurofeedback (BEHAVIORAL).
Who is sponsoring clinical trial NCT06219681?
This trial is sponsored by Laureate Institute for Brain Research, which has 45 total clinical trials registered on ClinicalTrials.gov.
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