H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute sponsors 502 registered US clinical trials on ClinicalTrials.gov, 82 of them currently recruiting, and 280 completed. 5 of these trials are in Phase 3-4 (later-stage) and 335 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 12 trials.
Trial Pipeline
502 total, page 3 of 11
Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma
NCT05628883
The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
NCT05692596
Early Supportive Care and Nutritional Support in Adults With Pancreatic Cancer
NCT05438927
Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Gastroesophageal Cancer (GEC) Patients
NCT05438940
Exercise to Boost Response to Checkpoint Blockade Immunotherapy
NCT05358938
"COACH" Study: Individualized COaching in Young Adult Cancer Survivors to Encourage Healthy Behaviors
NCT05434702
Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant
NCT05271630
Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCT
NCT05015426
Preop fSRS for Resectable Brain Metastases
NCT05267587
DASH INtervention to INvestigate the Gut
NCT04538482
Fedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL)
NCT05177211
Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization
NCT04879940
First Strike, Second Strike Therapies for High Risk Metastatic Castration Sensitive Prostate Cancer
NCT05189457
Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma
NCT05108428
Automated Video-Assisted Smoking Treatment for People Living With HIV
NCT05014282
Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma
NCT05170334
Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers
NCT05004662
Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma
NCT04975152
Capecitabine In Combination With Cemiplimab In Patient With Metastatic Breast Cancer
NCT05064085
Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools
NCT04335799
Evaluating Stress Management Among Allogeneic HCT Caregivers
NCT05078229
NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies
NCT04955730
Neoadjuvant Lenvatinib Plus Pembrolizumab in Merkel Cell Carcinoma
NCT04869137
Combination of Ipi/Nivo Plus Sacituzumab Govitecan in Metastatic Cisplatin Ineligible Urothelial Carcinoma Patients
NCT04863885
Canakinumab With Darbepoetin Alfa in PTs With Lower-Risk MDS Who Have Failed ESA
NCT04798339
Optimizing Cellular and Humoral Immunity by Vaccinating With PCV13 Before and After CAR-T Therapy
NCT04745559
Evolutionary Therapy for Rhabdomyosarcoma
NCT04388839
Clinical Trial of Green Tea Catechins in Men on Active Surveillance
NCT04300855
Quality of Life Model for Older Patients With AML
NCT04380441
Colorectal Cancer Awareness, Research and Education and Screening - Rural Expansion, Access and Capacity for Health
NCT04464668
Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma
NCT04151667
Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors
NCT03610971
Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma
NCT03628209
Use of 68Ga-dotatate PET Scan in Neuroendocrine Carcinoma of the GI Tract
NCT04069299
Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion
NCT03722407
Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer
NCT03923270
Phase II Trial to Modulate Intermediate Endpoint Biomarkers in Former and Current Smokers
NCT03598309
Florida Pancreas Collaborative Next Generation Biobank
NCT03851133
Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLC
NCT03611738
SBRT and Atezolizumab in the Management of Recurrent, Persistent, or Metastatic Cervical Cancer
NCT03614949
Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy
NCT03543189
Intermittent Androgen Deprivation Therapy for Stage IV Castration Sensitive Prostate Cancer
NCT03511196
Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma
NCT03543969
HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer
NCT03387553
Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer
NCT03384914
Phase I/II Study of Nivolumab and Ipilimumab Combined With Nintedanib in Non Small Cell Lung Cancer
NCT03377023
Randomized Study of Nivolumab+Ipilimumab+/- SBRT for Metastatic Merkel Cell Carcinoma
NCT03071406
XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma
NCT02721459
Validation Study on the Impact of Decipher® Testing - VANDAAM Study
NCT02723734
Pembro and Vorinostat for Patients With Stage IV Non-small Cell Lung Cancer (NSCLC)
NCT02638090
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 167 |
| Phase 2 | 168 |
| Phase 3 | 3 |
| Phase 4 | 2 |
Therapeutic Areas
What the Pipeline for H. Lee Moffitt Cancer Center and Research Institute Shows
According to the ClinicalTrials.gov registry, H. Lee Moffitt Cancer Center and Research Institute is linked to 502 US clinical trials across every stage of research activity. Of those, 82 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 280 are already marked complete, representing roughly 56% of the total.
The phase mix for H. Lee Moffitt Cancer Center and Research Institute reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 335 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for H. Lee Moffitt Cancer Center and Research Institute is Prostate Cancer with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.