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NCT03722407 · ClinicalTrials.gov registry record · Phase 2

Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion

A Phase 2 study of Leukemia and Chronic Myelomonocytic Leukemia, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Active
Registry status
Phase 2
Development phase
29
Enrollment target
5
Study locations

NCT03722407 is a Phase 2 study of Leukemia and Chronic Myelomonocytic Leukemia that is active but no longer recruiting, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 29 participants, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (94% lower). The trial reports 5 study locations across 5 states.

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The verdict

NCT03722407, a Phase 2 study of Leukemia and Chronic Myelomonocytic Leukemia, is active but no longer recruiting, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
29 participants
Enrollment target
5
Study locations

Study Summary

This study is to find out if treating Chronic Myelomonocytic Leukemia (CMML) with a study drug (ruxolitinib) can improve outcomes of patients with CMML.

Interventions

  • DRUG Ruxolitinib

Study Locations (5)

Florida

  • H. Lee Moffitt Cancer Center and Research Institute - Tampa

Maryland

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center - Baltimore

Massachusetts

  • Dana Farber Cancer Institute - Boston

New York

  • Weill Medical College of Cornell University - New York

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2019-08-28
Est. Completion 2026-06-01
Phase Phase 2

What the Registry Record Tells You About NCT03722407

The ClinicalTrials.gov registry entry for NCT03722407 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 487-participant average among 233 other Leukemia trials with a reported enrollment target (94% lower). The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Leukemia appearing as the primary indexed condition, and to 1 intervention - of which Ruxolitinib is the first listed.

NCT03722407 reports 5 study locations spanning 5 distinct geographic areas - top geographies include Florida, Maryland, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT03722407 about?

NCT03722407 is a clinical study titled "Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion". This study is to find out if treating Chronic Myelomonocytic Leukemia (CMML) with a study drug (ruxolitinib) can improve outcomes of patients with CMML.

What is the current status of trial NCT03722407?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2019-08-28. Estimated completion is 2026-06-01.

What conditions does trial NCT03722407 study?

This clinical trial studies the following conditions: Leukemia, Chronic Myelomonocytic Leukemia.

What interventions are being tested in trial NCT03722407?

The interventions under investigation include: Ruxolitinib (DRUG).

Who is sponsoring clinical trial NCT03722407?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03722407 being conducted?

This trial has 5 study locations across Florida, Maryland, Massachusetts, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.