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NCT03377023 · ClinicalTrials.gov registry record · Phase 1

Phase I/II Study of Nivolumab and Ipilimumab Combined With Nintedanib in Non Small Cell Lung Cancer

A Phase 1 study of Non-Small Cell Lung Cancer and Non Small Cell Lung Cancer Metastatic, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Active
Registry status
Phase 1
Development phase
66
Enrollment target
1
Study location

NCT03377023 is a Phase 1 study of Non-Small Cell Lung Cancer and Non Small Cell Lung Cancer Metastatic that is active but no longer recruiting, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 66 participants, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03377023, a Phase 1 study of Non-Small Cell Lung Cancer and Non Small Cell Lung Cancer Metastatic, is active but no longer recruiting, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
66 participants
Enrollment target
1
Study location

Study Summary

The main purpose of this study is to see if the combination of nivolumab, ipilimumab and nintedanib is effective in people with non- small cell lung cancer. Researchers also want to find out if the combination of nivolumab, ipilimumab and nintedanib is safe and tolerable.

Interventions

  • DRUG Nivolumab
  • DRUG Ipilimumab
  • DRUG Nintedanib

Study Locations (1)

Florida

  • H. Lee Moffitt Cancer Center and Research Institute - Tampa

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2018-02-02
Est. Completion 2026-08
Phase Phase 1

What the Registry Record Tells You About NCT03377023

The ClinicalTrials.gov registry entry for NCT03377023 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (90% lower). The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 3 interventions - of which Nivolumab is the first listed.

NCT03377023 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT03377023 about?

NCT03377023 is a clinical study titled "Phase I/II Study of Nivolumab and Ipilimumab Combined With Nintedanib in Non Small Cell Lung Cancer". The main purpose of this study is to see if the combination of nivolumab, ipilimumab and nintedanib is effective in people with non- small cell lung cancer. Researchers also want to find out if the combination of nivolumab, ipilimumab and nintedanib is safe and tolerable.

What is the current status of trial NCT03377023?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 66 participants. The study started on 2018-02-02. Estimated completion is 2026-08.

What conditions does trial NCT03377023 study?

This clinical trial studies the following conditions: Non-Small Cell Lung Cancer, Non Small Cell Lung Cancer Metastatic, Lung Cancer, Nonsmall Cell.

What interventions are being tested in trial NCT03377023?

The interventions under investigation include: Nivolumab (DRUG), Ipilimumab (DRUG), Nintedanib (DRUG).

Who is sponsoring clinical trial NCT03377023?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03377023 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.