Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 2 of 35
Hospital-to-Home Transitional Care Interventions (H2H-TCI) Children/Youth With Special Health Care Needs (CYSHCN)
NCT06428175
Optimizing Timing of Cesarean Delivery Consent on Labor and Delivery
NCT07117708
HCMT/MM2401: Ph2 Study of Selinexor + Bispecific Antibody for RRMM
NCT06822972
AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance
NCT06619405
Pain With Dementia
NCT06854718
COMPASS Study for Metastatic Castration-resistant Prostate Cancer
NCT07050433
4D Duke Microscope Integrated Optical Coherence Tomography in a Zeiss Artevo 800
NCT07024719
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
NCT06909565
Targeted Remotely-delivered Anti-inflammatory Interventions With Exercise for Rheumatoid Arthritis
NCT06841562
Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
NCT06371768
SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families
NCT06627764
Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors
NCT06732375
Engage Psychosocial Intervention for Cancer Symptoms
NCT06555588
The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.
NCT06765642
DBT-P Treatment Study
NCT06963801
Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery
NCT06962306
Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition
NCT06971640
Assessing Better Bottles for Babies
NCT06357299
Urine Methylation Markers in UTUC
NCT06805630
Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs
NCT06545643
Coping Skills Training for Symptom Management and Daily Steps (Step Up)
NCT06575712
Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery
NCT06986967
Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae
NCT06815536
Opioids, Low Nicotine Cigarettes, and Chronic Pain
NCT06747871
Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction
NCT06733012
Role of Aging and Individual Variation in Exercise Training Responsiveness
NCT06471569
Ultrasound Simulation Case-based Workshop Implementation and Impact Assessment
NCT06960837
Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer
NCT06636721
Effect of Acetylcholinesterase Inhibitors on Bone Metabolism
NCT06041789
Collecting Outcomes and Managing Pain After Surgery
NCT03834818
Olfactory Biopsies
NCT07021040
OUD (Opioid Use Disorder) Target Trial
NCT06585709
Rare Glycogen Storage Diseases Natural History Study
NCT06795152
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
NCT06625684
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
NCT06576830
GERD in Children With Cystic Fibrosis
NCT06617013
Tolerability of an Anesthesia-free Tonometer Tip
NCT06585423
Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
NCT06538246
PK/PD of Digoxin in Infants With SVHD
NCT06613477
Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?
NCT06471036
Imaging Retinal Vasculature in Infant Eyes
NCT05558059
Cancer and Mild Cognitive Impairment Dyadic Intervention
NCT05144516
Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes
NCT06399302
Bacterial Decolonization Within Dyads
NCT06541145
Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)
NCT05945355
Predictors of Pain in Sickle Cell Disease
NCT06139510
Intervention to Improve Communication and Medication Adherence in Lupus
NCT06458075
Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252
NCT06126744
Nutrition and Obesity in Under-Represented Populations: Food Insecurity Research to Advance Science and Improve Health
NCT06116422
Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study
NCT06333925
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.