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NCT06962306 · ClinicalTrials.gov registry record · Phase 4
Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery
A Phase 4 study of Pain and Children, sponsored by Duke University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06962306: Recruiting Phase 4 study of Pain and Children, sponsored by Duke University.
NCT06962306 is a Phase 4 study of Pain and Children that is actively recruiting participants, run by Duke University. The registered enrollment target is 60 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06962306, a Phase 4 study of Pain and Children, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.
Primary Outcome
Post-PACU in-hospital opioid use in oral morphine milligram equivalents (OMEs) per kilogram through POD1
Conditions Studied
Interventions
- DRUG Methadone hydrochloride
- DRUG Fentanyl/Hydromorphone
Study Locations (1)
North Carolina
- Duke University Medical Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-06-04 |
| Est. Completion | 2027-07-04 |
| Phase | Phase 4 |
What NCT06962306 shows while recruiting
NCT06962306 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (80% lower).
The record links to 5 conditions, with Pain appearing as the primary indexed condition, and to 2 interventions - of which Methadone hydrochloride is the first listed.
NCT06962306 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06962306 about?
NCT06962306 is a clinical study titled "Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery". The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.
What is the current status of trial NCT06962306?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2025-06-04. Estimated completion is 2027-07-04.
What conditions does trial NCT06962306 study?
This clinical trial studies the following conditions: Pain, Children, Cleft Palate, Postoperative Care, Perioperative Care.
What interventions are being tested in trial NCT06962306?
The interventions under investigation include: Methadone hydrochloride (DRUG), Fentanyl/Hydromorphone (DRUG).
Who is sponsoring clinical trial NCT06962306?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06962306 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06962306's enrollment target sits among peer trials
60 224th of 374 higher than 134 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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