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NCT06747871 · ClinicalTrials.gov registry record · NA
Opioids, Low Nicotine Cigarettes, and Chronic Pain
A NA study of Chronic Pain and Tobacco Use, sponsored by Duke University.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06747871: Recruiting NA study of Chronic Pain and Tobacco Use, sponsored by Duke University.
NCT06747871 is a NA study of Chronic Pain and Tobacco Use that is actively recruiting participants, run by Duke University. The registered enrollment target is 60 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06747871, a NA study of Chronic Pain and Tobacco Use, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain who smoke cigarettes daily and are attending office-based buprenorphine treatment (OBBT).
Primary Outcome
The FTCD has a total score of 0 to 10, where a greater score indicates a greater physical dependence on nicotine.
Conditions Studied
Interventions
- BEHAVIORAL Very Low Nicotine Cigarettes (VLNC)
- BEHAVIORAL Normal Nicotine Cigarettes (NNC)
Study Locations (1)
North Carolina
- North Pavilion - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-04-15 |
| Est. Completion | 2027-07-30 |
| Phase | NA |
What NCT06747871 shows while recruiting
NCT06747871 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (92% lower).
The record links to 3 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Very Low Nicotine Cigarettes (VLNC) is the first listed.
NCT06747871 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06747871 about?
NCT06747871 is a clinical study titled "Opioids, Low Nicotine Cigarettes, and Chronic Pain". The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain who smoke cigarettes daily and are attending office-based buprenorphin...
What is the current status of trial NCT06747871?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-04-15. Estimated completion is 2027-07-30.
What conditions does trial NCT06747871 study?
This clinical trial studies the following conditions: Chronic Pain, Tobacco Use, Opioid Substitution Treatment.
What interventions are being tested in trial NCT06747871?
The interventions under investigation include: Very Low Nicotine Cigarettes (VLNC) (BEHAVIORAL), Normal Nicotine Cigarettes (NNC) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06747871?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06747871 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06747871's enrollment target sits among peer trials
60 176th of 301 higher than 112 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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