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RECRUITING NA

Opioids, Low Nicotine Cigarettes, and Chronic Pain

NCT06747871 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain who smoke cigarettes daily and are attending office-based buprenorphine treatment (OBBT).

Interventions

  • BEHAVIORAL Very Low Nicotine Cigarettes (VLNC)
  • BEHAVIORAL Normal Nicotine Cigarettes (NNC)

Study Locations (1)

North Carolina

  • North Pavilion — Durham

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-04-15
Est. Completion 2027-07-30
Phase NA

Sponsor

Duke University

1,129 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06747871

The ClinicalTrials.gov registry entry for NCT06747871 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,129 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions — of which Very Low Nicotine Cigarettes (VLNC) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06747871 reports 1 study location spanning 1 distinct geographic area — top geographies include North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06747871 about?

NCT06747871 is a clinical study titled "Opioids, Low Nicotine Cigarettes, and Chronic Pain". The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain who smoke cigarettes daily and are attending office-based buprenorphin...

What is the current status of trial NCT06747871?

This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-04-15. Estimated completion is 2027-07-30.

What conditions does trial NCT06747871 study?

This clinical trial studies the following conditions: Chronic Pain, Tobacco Use, Opioid Substitution Treatment. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06747871?

The interventions under investigation include: Very Low Nicotine Cigarettes (VLNC) (BEHAVIORAL), Normal Nicotine Cigarettes (NNC) (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06747871?

This trial is sponsored by Duke University, which has 1,129 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06747871 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial