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NCT06333925 · ClinicalTrials.gov registry record · NA
Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study
A NA study of Anxiety Disorder and Misophonia, sponsored by Duke University.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06333925 is a NA study of Anxiety Disorder and Misophonia that is actively recruiting participants, run by Duke University. The registered enrollment target is 60 participants, below the 422-participant average among 20 other Anxiety Disorder trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06333925, a NA study of Anxiety Disorder and Misophonia, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Misophonia, the inability to tolerate certain repetitive distressing sounds that are common, is gaining, recognition as an impairing condition. It is not a well-understood condition and there are no known treatments. The purpose of this study is to test a new misophonia intervention that uses emotion regulation strategies and different types of brain stimulation on misophonic distress. This study will examine changes in brain activity during presentation and regulation of misophonic versus distressing sounds. The study team plans to alter activity in a key area of the brain responsible for emotion regulation circuitry over 4 sessions with the goal to test if this intervention helps misophonic distress. Sixty adult participants with moderate to severe misophonia will be recruited and taught an emotion regulation skill and randomly assigned to receive one of two types of repetitive transcranial magnetic stimulation (rTMS). The study includes 9-10 visits: the remote screening visit(s), the initial MRI, the four neurostimulation sessions, the follow-up MRI, and two additional remote 1- and 3-month follow-up visits.
Conditions Studied
Interventions
- DEVICE High Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS)
- DEVICE Sham Repetitive Transcranial Magnetic Stimulation (sham- rTMS)
- BEHAVIORAL Cognitive Restructuring
Study Locations (1)
North Carolina
- Duke University Medical Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-05-14 |
| Est. Completion | 2026-11-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06333925
The ClinicalTrials.gov registry entry for NCT06333925 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 422-participant average among 20 other Anxiety Disorder trials with a reported enrollment target (86% lower). The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with Anxiety Disorder appearing as the primary indexed condition, and to 3 interventions - of which High Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS) is the first listed.
NCT06333925 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT06333925 about?
NCT06333925 is a clinical study titled "Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study". Misophonia, the inability to tolerate certain repetitive distressing sounds that are common, is gaining, recognition as an impairing condition. It is not a well-understood condition and there are no known treatments. The purpose of this study is to test a new misophonia intervention that uses emotio...
What is the current status of trial NCT06333925?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-05-14. Estimated completion is 2026-11-30.
What conditions does trial NCT06333925 study?
This clinical trial studies the following conditions: Anxiety Disorder, Misophonia, Sensory Processing Disorder, Emotion Dysregulation, Auditory Over Responsivity.
What interventions are being tested in trial NCT06333925?
The interventions under investigation include: High Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS) (DEVICE), Sham Repetitive Transcranial Magnetic Stimulation (sham- rTMS) (DEVICE), Cognitive Restructuring (BEHAVIORAL).
Who is sponsoring clinical trial NCT06333925?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06333925 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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